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感染性疾病血清学检验中应重视对弱反应性标本的确认 被引量：126

Attention to the confirmative tests of weak reactive samples should be paid in serological testing for infectious diseases
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摘要 感染性疾病免疫血清学检验中,由于阳性判断值设定的问题及标本中可能存在的干扰因素,免疫测定中的弱反应性很有可能为假阳性。确认方法可分为特异抗原确认的中和试验和特异抗体确认的免疫印迹或荧光抗体试验。建立对弱反应性标本确认程序,对于感染性疾病临床诊断和人群体检的正确性有重要意义。 It is possible that weak-reactive is false positive in serological testing for infectious diseases because of the uncertainty of cut-off values used and some interference factors of clinical samples. The confirmative tests of weak-reactive samples included neutralization assay for specific antigen and immuno-blotting or immuno-fluorescence antibody assay for specific antibody. It is important to set up confirmative procedures for weak-reactive samples in clinical diagnosis of infectious diseases and body examination of normal population.
作者 李金明
机构地区 卫生部北京医院卫生部临床检验中心
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2006年第7期577-580,共4页 Chinese Journal of Laboratory Medicine
关键词 感染性疾病 血清学检验 反应性 标本 荧光抗体试验 疾病免疫 免疫测定 免疫印迹 特异抗体 中和试验
分类号 R51 [医药卫生—内科学] R446.11 [医药卫生—诊断学]
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参考文献13

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二级参考文献17

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共引文献15

同被引文献633

引证文献126

二级引证文献526

中华检验医学杂志
2006年 第7期

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