摘要
目的观察急性心肌梗死(AMI)患者入院前后血清肌钙蛋白I(cTnI),心肌肌酸激酶同工酶MB(CK-MB)测定值的变化。探讨cTnI对早期诊断AMI的价值。方法对50例AMI患者和50例健康人血清进行cTnI和CK—MB的检测。结果 AMI后3h内cTnI阳性检出率94．0％,明显高于CK-MB24．0％,AM15d后cTnI阳性84．0％,而CK-MB仅为6．0％。结论血清cTnI能早期确切诊断AMI,具有较宽的诊断窗,是急性心肌梗死早期诊断较敏感和特异的血清标志物。
Objective To investigate the early diagnostic value and significance of cardiac troponin Ⅰ（cTnⅠ） and CK-MB in acute myocardial infarction （AMI）.Methods Serum from 50 patients with coronary heart disease （AMI） and 50 healthy were examined for cTnI and CK-MB.Results In the 3h after AMI, the positive rates ofcTnl 94.0% were significantly higher than CK-MB.24.0%, in the 5 day after AMI, the positive rates were 84.0% for cTnl and CK-MB were 6.0%.Conclusion The serum level of cTnI can closely reflect of myocardial dagmage in AMI. It provides a early diagnostic window. Serum level of cTnI is a marker high sensitivity and specificity for AMI and can aid in the early diagnosis of AMI.
出处
《中国血液流变学杂志》
CAS
2006年第2期286-287,共2页
Chinese Journal of Hemorheology
