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泌尿道感染大肠埃希菌耐药性分析

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摘要 目的了解医院泌尿道感染大肠埃希菌产ESBLs的发生率和耐药情况。方法据NCCLS文件,产ESBLs细菌的检测用双纸片确认法,抗生素敏感测定采用K-B琼脂扩散法。结果在检出的176株大肠埃希菌中,ESBLs阳性的菌株有53例,ESBLs检出率为30.1%。检出的产ESBLs细菌对所有青霉素类抗生素产生耐药,产ESBLs对3代头孢类抗生素头孢曲松、头孢噻肟的耐药率>81%,对磺胺类、喹诺酮类也在71%以上。对亚胺培南全部敏感。结论医院泌尿道大肠埃希菌产ESBLs发生率较高,且对多种抗生素呈交叉耐药和多重耐药,应做好常规检测和监测,指导临床合理使用抗生素。
作者 刘旭忠 詹贞芳 宋智盛 李毅 谢必会
机构地区 丹江口市汉江医院
出处 《中国微生态学杂志》 CAS CSCD 2006年第4期318-318,321,共2页 Chinese Journal of Microecology
关键词 超广谱Β-内酰胺酶 耐药性 抗生素
分类号 R378.21 [医药卫生—病原生物学]
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中国微生态学杂志
2006年 第4期

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