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双水平气道正压通气治疗慢性阻塞性肺病Ⅱ型呼吸衰竭

BiPAP therapy for type Ⅱ respiratory failure in chronic obstructive pulmonary disease
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摘要 目的:探讨双水平气道正压通气治疗慢性阻塞性肺病Ⅱ型呼吸衰竭的临床疗效。方法:对35例慢性阻塞性肺病Ⅱ型呼吸衰竭的患者采用双水平气道正压通气进行治疗,分析无创正压通气(NIPPV)治疗前后动脉血pH值、动脉血氧分压(PaO2)、动脉血二氧化碳(PaCO2)、心率(HR)、呼吸频率(RR)等指标的变化。结果:实施NIPPV 3 h后即能改善患者的动脉血pH值、PaO2、PaCO2,减慢HR、RR;治疗72 h后与通气前比较差异有统计学意义(P均<0.01)。结论:使用NIPPV治疗慢性阻塞性肺病Ⅱ型呼吸衰竭疗效确切,且使用时间长效果更好。 Objective: To study the effection of BiPAP therapy on type Ⅱ respiratory failure patients resulted by chronic obstructive pulmonary disease. Method: Artery blood gas analysis were performed for 35 COPD patients under BiPAP therapy before and after ventilation respectively. Results: Succeed rate of NIPPV was 91.43%. Invasive ventilation through endotracheal intubation was given to three patient who was failued in NIPPV therapy, pH, PaO2, PaCO2 were improved prominently after 3 hours ventilation therapy. Conclusion: NIPPV therapy has reliable curative effect on the patients of type Ⅱ respiratory failure in chronic obstructive pulmonary disease (COPD).
出处 《新疆医科大学学报》 CAS 2006年第7期598-599,共2页 Journal of Xinjiang Medical University
关键词 慢性阻塞性肺病(COPD) Ⅱ型呼吸衰竭 NIPPV COPD respiratory failure: NIPPV
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