摘要
目的:评价支气管动脉灌注(bronchial arterial infusion,BAI)化疗药物治疗中晚期肺癌的疗效及安全性。方法:对40例中晚期肺癌患者行支气管动脉插管,通过支气管动脉灌注化疗药物。采用顺铂(DDP)50mg^60mg或卡铂(CBP)300mg^500mg、丝裂霉素(MMC)10mg和阿霉素(ADM)50mg三联药物,40例共行88次BAI治疗。结果:40例患者中完全缓解(CR)4例,部分缓解(PR)24例,稳定(SD)9例,进展(PD)3例,有效率(CR+PR)为70.0%,1a生存率为62.5%。鳞癌和富血供肺癌的BAI疗效分别优于腺癌和乏血供者(P<0.01)。结论:支气管动脉灌注治疗中晚期肺癌安全有效。
Objective clinical chemotherapy effect and safety of bronchial arterial infusion （BAI） in the mid-advanced lung cancer. Methods Forty patients of mid-advanced lung cancer confirmed by pathologhy received BAI treatment. In the combination of chemotherapy medicine,they were DDP （50 mg- 60 mg） or CBP （300 mg-500 mg）, MMC （10 mg） and ADM （50 mg）. There were total 88 BAI in 40 patients. Results In 40 patients,there were 4 cases of complete response,24 cases of partial response,9 steady cases and 3 advanced cases. The curative results were 28 cases （70.0%） and one-year-survival rate was 62.5 %. The chemotherapy effect of squamous carcinoma and sufficient-blood tumor was better than that of adenocarcinoma and insufficient-blood tumors, respectively （P〈0.01）. Conclusion BAI is an effective and safe method of treating the mid-advanced lung cancer.
出处
《实用医技杂志》
2006年第13期2202-2203,共2页
Journal of Practical Medical Techniques
关键词
肺癌
支气管动脉
治疗
Lung tumor Arteries of bronchus Therapy
