摘要
采用ＲＩＡ法对５８例良、恶性胸腔积液中ＥＧＦ与ＴＮＦ进行含量检测。结果显示２２例良性胸水中ＥＧＦ与ＴＮＦ含量分别为２．０３±０．３５μｇ／Ｌ，１．６３±０．５４μｇ／Ｌ。３６例恶性胸水中ＥＧＦ与ＴＮＦ含量分别为１．２５±０．３２μｇ／Ｌ，１．０２±０．２４μｇ／Ｌ。良性胸水组ＥＧＦ与ＴＮＦ浓度均明显高于恶性胸水组，两组间有显著性差异，（Ｐ＜０．０５）。结果表明ＥＧＦ与ＴＮＦ均参与了良、恶性胸腔积液的免疫病理生理过程。
Using radioimmunoassay the levels of epidermal growth factor (EGF) and tumor necrosis factor (TNF) in benign or malignant pleural effusions of 58 patients were determined. EGF and TNF levels in benign pleural effusions were 2. 03±0. 35ng/L and 1. 63±0. 54ng/L respectively and were 1. 25±0. 32ng/L and 1.02±0.24ng/L respectively in malingant pleural effusions. Both the EGF and TNF levels in benign pleural effusions were markedly higher than those in malignant pleural effusions (P<0. 05). It suggests that EGF and TNF may play an important role immunopathologically in the formation of benign and malignant pleural effusions.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1996年第10期692-694,共3页
Chinese Journal of Clinical Oncology
关键词
表皮生长因子
肿瘤坏死因子
胸腔积液
Epidermal Growth Factor (EGF) Tumor Necrosis Factor (TNF) Pleural effusion
