摘要
目的：探讨对临床Ⅰ期卵巢上皮性癌患者施行全面分期探查术的重要意义。方法：对４３例临床Ⅰ期卵巢癌患者的临床、病理及随访资料进行回顾性研究。依据国际妇产科联盟（ＦＩＧＯ）的分期标准，对照分析经全面分期探查术后确定为ＦＩＧＯⅠ期卵巢癌３２例（Ａ组），经全面分期探查术后升级为Ⅲ期的卵巢癌５例（Ｂ组）和未经全面分期探查术、临床分期为Ⅰ期卵巢癌６例（Ｃ组）的临床治疗结果和预后。结果：经过全面分期探查术的患者中，１３．５％（５／３７）发现有腹膜后淋巴结转移，因此，期别上升为Ⅲ期。分期探查术平均手术时间为２小时４０分钟，术中平均出血量为４６０ｍｌ，无１例发生严重并发症。在平均为３９．７个月的随诊中，Ａ组无瘤生存率为９７％（３１／３２）；Ｂ组无瘤生存率为５／５，而Ｃ组中２例复发，其中１例死亡，无瘤生存率为４／６。比较Ａ、Ｃ两组无瘤生存率，差异有显著性（Ｐ＝０．０３８）。结论：全面分期探查术的结果是卵巢癌ＦＩＧＯ分期的重要依据。对临床分期为Ⅰ期的卵巢癌患者应常规进行全面分期探查术。
Objective:ToevaluatethesignificanceofcomprehensivestaginglaparotomyinstageIepithelialovariancancer.Methods:Forty-threepatientswithstageIepithelialovariancancerweredividedinto3groupsandretrospectivelyanalysed.ThirtytwoofthesepatientsalotedtostageIo-variancanceraccordingtoFIGOcriteriawereascertainedbycomprehensivestaginglaparotomy(groupA),5patientswereupstagedfolowingcomprehensivestaginglaparotomy(groupB)and6patientswerestagedwithoutcomprehensivelaparotomy(groupC).Results:Themeanoperationtimewas2hoursand40minutes,themeanvolumeofbloodlosswas460mlandnoseverecomplica-tionsoccurredduringthecomprehensivestaginglaparotomies.13.5%(5/31)ofpatientswerefoundtohaveretroperitonealmetastasisandthenthereforewereupstagedasstageII.GroupAandBhadbeterprognosis.Duringthe39.7monthsfolowupperiod,tumor-freesurvivalratesingroupAandBwere97%(31/37)and5/5respectively.IngroupC,2patientsrecurentandonediedofthedis-eases,atumor-freesurvivalratesof4/6.Therewasasignificantdiferenceintumor-freesurvivalratesbwtwengroupAandC(P=0.038).Conclusion:ComprehensivestaginglaparotomyshouldbeconsideredasanimportantcriterioninFIGOstagingofepithelialovariancancerandastandardprocedureinthetreatmentofstageIepithelialovariancancer.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1996年第7期390-394,共5页
Chinese Journal of Obstetrics and Gynecology
关键词
肿瘤分期
卵巢肿瘤
探查术
NeoplasmsstagingOvarianneoplasmsCarcinoma
