摘要
目的:探讨移居高原居住不同时间尿生化指标的变化。方法:对移居海拔4 300 m高原3个月(103人)、6个月(70人)及1年(106人)的男性汉族健康青年,采用自动尿分析仪进行晨尿11项指标分析。结果:移居高原者尿11项指标均有异常出现,主要以尿蛋白、尿潜血、白细胞居多。尿蛋白、尿潜血和白细胞在移居高原3个月较6个月和1年以上的阳性率均增高(P<0.01或0.05);6个月与1年以上比较无统计学意义(P>0.05)。结论:高原低氧环境对肾脏的损害是随着居住时间的延长而减弱。低氧导致肾小管重吸收功能降低和肾小球透性增强。
Objective：To explore the changes of biochemical indexes in urine of migrants living at high altitude for different times. Methods： 11 biochemical indexes in urine of 103 migrants having lived at 4 300 m altitude for 3 months, of 70 ones having lived at 4 300 m altitude for 6 months and of 106 ones having lived at 4 300 m altitude for 12 months. Results：All of these 11 indexes were abnormal, especially protein, occult blood and white cell. The levels of protein, occult blood and white cell in urine of the subjects living for 3 months were higher than those in urine of the subjects living for 6 months and 12 months（P〈0. 01 or 0. 05）. But the difference of above indexes between living for 6 months and 12 months was not significant（P〉0. 05）. Conclusion： Hypoxie environment may weaken the re - absorption of renal tubule and enhance glomerulus＇s permeability, but these effects of hypoxia on the renal function will become weaker as migrants live at high altitude longer.
出处
《西南国防医药》
CAS
2006年第4期369-370,共2页
Medical Journal of National Defending Forces in Southwest China
关键词
高原
尿分析
尿蛋白
high altitude, urinalysis, biochemistry, migrant
