摘要
目的探讨急性冠脉综合征(ACS)病人血清胆红素变化的临床意义。方法108例ACS病人分为ST段抬高的心肌梗死组(STEM I组,40例),非ST段抬高的心肌梗死组(NSTEM I组,30例),不稳定型心绞痛组(UAP组,38例),对照组45例为健康查体人员。108例病人中66例行冠状动脉造影后分为单支病变组(26例),双支病变组22例,三支病变组(18例),选择同期冠状动脉造影正常的30例非冠心病病人作为对照组。以上各组均测定血清总胆红素、直接胆红素等临床指标。结果对照组总胆红素、直接胆红素均高于其他各组(P<0.05);其中UAP组高于STEM I组(P<0.05)。造影正常组血清胆红素也高于其他三组(P<0.05),单支病变组高于多支病变组(P<0.05)。结论ACS病人血清胆红素低于正常人,低血清胆红素水平可能与ACS患者病情严重程度有关。
Objective To study the clinical significance of serum bilirubin in patients with acute coronary syndrome（ACS）. Methods One hundred and eight paitents with ACS were classified into STEMI group（ n =40） ,NSTEMI group（ n =30） ,UAP group（ n = 38）. There were 45 health subjects in control group. Of 108 paitents,66 performed with coronary angiography were grouped into 1 - vessel - disease（ n = 26） ,2 - vessel - disease（ n = 22） ,3 - vessel - disease（ n = 18）. Total bilirubin （TBIL） and direct bilirubin（DBIL） were determined in all the subjects. Results The serum levels of TBIL and DBIL in control group were higher than in orther groups （ P 〈 0. 05 ） , also they were higher in UAP group than in STEMI group （ P 〈 0. 05 ）. In control group with normal angiographic findings, the levels of bilirubin were higher than in 30 vessel - disease groups （ P 〈 0. 05 ） ,in 3 - vessel - disease group they were lower than in 1 - vessel - disease group （ P 〈 0. 05 ）. Conclusion The levels of serum bilirubin in paitents with ACS were lower than in healthy people, it may have connection with severe conditions in paitents with ACS.
出处
《临床医学》
CAS
2006年第8期72-74,共3页
Clinical Medicine
