摘要
目的探讨经皮动脉血管灌注药物治疗股骨头缺血性坏死的临床应用价值。方法运用Seldinger技术,对45例股骨头缺血性坏死患者,进行选择性动脉造影、超选择动脉血管灌注溶通药物。结果45例患者在治疗后髋部疼痛及关节功能障碍均有不同程度减轻和改善,随访2a,X线平片示20岁以下的青少年患者坏死股骨头骨质均已完全修复,老年患者及IV级以上患者骨质修复差。未发生与操作本身有关的严重并发症。结论经皮动脉血管灌注溶通药物治疗青少年及Ⅰ级～Ⅲ级股骨头缺血性坏死效果明显,风险小,是一种值得临床应用的技术。
Objective To study the therapeutic effects of percutaneous intraartery infusion of thrombolytic drugs on the avascular necrosis of femoral head （ANFH）. Methods Forty - five patients with ANFH underwent selective digital subtraction angiography （DSA） and superselective intraartery infusion of thrombolytic drugs. The procedure was performed by using Seldinger＇s technique. Results After the interventional therapy, all patients were followed up for 2 years. The clinical symptom of hip pain in most patients were alleviated even disappeared, while the function of affected joints was obviously improved. At 2 year after interventional therapy, X - ray plain films showed that, the osteonecrosis of femoral head in young patients who were less than 20 years old was already completely repaired but that in old patients or grade Ⅳ of ANFH was poorly repaired. There were no severe complications related to the procedure in the study. Conclusion Percutaneous intraartery infusion of thrombolytic drugs has obvious effect for treating ANFH in young patients or ANFH below grade Ⅲ and therefore it is worth clinically wide application.
出处
《实用医学影像杂志》
2006年第4期252-254,共3页
Journal of Practical Medical Imaging
关键词
股骨头
缺血性坏死
溶栓药物
动脉内灌注
介入治疗
Femoral head
Avascular neorosis
Thrombolytic drug
Intraartery infusion
Interventional therapy
