摘要
在pH3．0的B-R缓冲液中，用吸附伏安法对阿昔洛韦进行了研究与测定。阿昔洛韦在＋1．25V（vs．Ag／AgCl）附近有一不可逆的氧化峰。线性范围为5×10^-6～1．5×10^-4mol／L，检出限为2．0×10^-6mol／L。用该法分析了实际试样，并与光谱法进行了比较，测定结果令人满意。还对阿昔洛韦的电极反应机理进行了初步探讨。实验结果表明，本法具有测定快速、准确，选择性好，重现性好等优点。
Aciclovir is oxidized at a glass carbon electrode in BR buffer （pH = 3. 0）by adsorptive voltammetry. The peak potential was about 1.25 V（vs. Ag/AgCl）. The linear range was 5×10^-6- 1.5×10^-4 mol/L, and the detection limit reached 2.0×10^-6 mol/L. Aciclovir in tablets was determined with good results by this method. The voltammetric behavior and reaction mechanism have been studied. It shows that it＇s an unreversible process with one electron and one proton transfered at glass carbon electrode.
出处
《分析科学学报》
CAS
CSCD
2006年第4期444-447,共4页
Journal of Analytical Science
关键词
阿昔洛韦
吸附伏安法
玻碳电极
Aciclovir
Adsorptive voltammetry
Glassy carbon electrod
