摘要
目的分析青少年屈光不正性弱视使用硬性透气角膜接触镜（rigid gas permeable，RGP）在三年中的视力矫正效果以及在屈光度、图形视觉诱发电位（pattern-visual evoked potential，P-VEP）方面的变化及其机制。方法对23例年龄≥12周岁屈光参差性弱视患者[男10例15眼，女13例17眼，平均年龄为（15．26±2．01）岁]在实验配戴RGP始末分别测定屈光度、矫正视力和P-VEP；所有RGP实验对象配戴镜片周期〉50周，且与同期20例青少年屈光不正性弱视框架镜验配者作对照。结果23例实验患者RGP验配适应时间为2～6d不等。至实验结束，近视球镜度RGP组增加-0．36Ds，柱镜度下降0．12Dc；框架镜对照组球镜度加深-0．81Ds；柱镜度无显著变化。实验末两组球镜度值比较，组间差值为0．55Ds（配对t检验P〈0．05）。矫正视力：RGP组与框架镜对照组实验前后自身对照，分别上升0．52±0．22和0．12±0．05（五分对数视力）。p-VEP检测：实验始末两组自身对照，P100波振幅无显著变化，P100波潜伏时两组分别缩短13ms和8ms，差异有显著性（配对t检验P〈0．01）。结论年龄≥12周岁青少年屈光不正性弱视可选择性地使用RGP，以提高弱视眼的矫正视力。
Objective To investigate the effects of wearing a rigid gas permeable contact lens （RGP） in teenage amblyopes who were older than 12 years and to study their refractive status and pattern-visual evoked potentials （P-VEP） during a long-term follow-up. Methods Twonty-three teenage amblyopes [ 15 eyes of 10 men, 17 eyes of 13 women, average age （ 15.26 3= 2.01）years] participated in the study. All of them had been examined to measure refractive power, visual acuity and P-VEP before and after RGPs were fitted. Each of them was requested to wear the RGPs for at least 50 weeks. As a control, the same testing was also done on mother group of 20 teenagers who wore spectacles. Results 2 - 6 days were needed to adapt to the RGPs. During three years of follow-up, there was an average inerease -0.36 Ds in the spherical component of refraction in the RGP group, and -0.81D in the spectacle group （paired t-test P 〈0.05）. Cylindrical power decreased - 0.12 De on average in the RGP group but did not change in the control group. Whon compared to pre-fitting, it was found that the P-VEP was shorter in P100 wave potential time （ 13 ms in the RGP group and 8 ms in the spectacle group, paired t-test P 〈 0.01）, but there was only a slight increase in the amplitde of the P100 wave. Conclusion Amblyopic teenagers can wear rigid gas permeable contact lenses on a daily basis.
出处
《眼视光学杂志》
2006年第4期252-254,共3页
Chinese Journal of Optometry & Ophthalmology
基金
浙江省科技计划项目(001103229)
