摘要
目的:利用彩色多谱勒(CDFI)对中医不同证型原发性肝癌(HCC)患者血流变化进行分析,为中医证候研究提供客观量化指标。方法:将114例HCC患者根据中医辨证分为脾虚肝郁型、气滞血瘀型、湿热蕴结型、湿瘀搏结型、肝肾阴虚型,利用CDFI观察肝固有动脉收缩期最大血流速度(Vmax)、阻力指数(RI)及门静脉每分钟血流量(Q)。结果:肝固有动脉Vmax临床Ⅱ、Ⅲ期与对照组比较,Ⅲ期与Ⅰ期比较,差异均有非常显著性意义(P<0．01)。门静脉QⅡ期显著增多,与对照组、Ⅰ期、Ⅲ期比较,差异均有非常显著性意义(P<0．01)。中医不同证型中湿瘀搏结型Vmax显著增高,与对照组及脾虚肝郁型比较,差异有非常显著性意义(P<0．01);其次为气滞血瘀型,与对照组比较,差异有显著性意义(P<0．05)。气滞血瘀型门静脉Q增多,与对照组及湿瘀搏结型比较,差异均有显著性意义(P<0．05)。肝固有动脉RI值临床分期、中医不同证型与对照组比较,差异均无显著性意义(P>0．05)。结论:CDFI不仅可对HCC进行诊断,且可对中医不同证型。HCC患者进行血流动力学分析,为中医证候的研究提供客观量化指标。
Objective: To analyze the changes of blood flow of hepato-cellular carcinoma (HCC) of different TCM syndrome by color Doppler flow imaging (CDFI) so as to supply objective quantitative parameter for study of TCM syndrome. Methods: 114 cases of HCC were allocated to spleen-deficiency and stagnation of liver-qi type (SDSLT), qi-stagnation and blood stasis type (QSBST), stagnation of damp-heat type (SDHT), collaboration of damp and blood-stasis type (CDBST) and yin-deficiency of liver and kidney type (YDLKT) in according to TCM syndrome differentiation, the Vmax of systole of hepatic artery, resistance index (RI) and per minute blood flow (Q) of portal vein were observed by CDFI. Results: The comparison of Vmax of hepatic artery of clinicalⅡandⅢstages with control group andⅢandⅠstages showed very markedly significant ( P < 0. 01). The comparison ofⅡstage Q of portal vein with control group andⅠandⅢstages showed very markedly significant (P < 0.01). Among different syndromes, the Vmax of CDBST was markedly increased, comparison with control group and SDSLT show very markedly significant (P < 0.01); comparison of QSBST with control group showed marked significance ( P < 0. 05). The Q of QSBST was increased, comparison with control group and CDBST showed marked significance ( P < 0. 05). The comparison of RI value in different TCM syndromes with control group showed no marked significance (P> 0. 05). Conclusion: CDFI not only acts for diagnosis of HCC but also serves for analysis of hemodynamics in different TCM syndromes of HCC and supply a subjective quantitative parameter for TCM syndrome.
出处
《新中医》
CAS
北大核心
2006年第9期22-23,共2页
New Chinese Medicine
