摘要
目的总结儿童传染性单核细胞增多症(IM)的临床特点。方法回顾性总结分析2001年1月~2005年12月深圳143例住院儿童传染性单核细胞增多症的临床资料。结果143例IM中,6岁及以下儿童占82.5%,其中,小于3岁儿童占49%。发热132例(92.3%),平均(6.88±3.26)d,81.1%在4d或以上,47.6%在7d或以上;咽峡炎138例(96.5%),有白色渗出物72例(50.3%);颈部淋巴结肿大88例(61.5%);肝肿大73例;脾肿大32例(22.4%);眼睑浮肿18例(12.6%)。102例(71.3%)异型淋巴细胞≥0.10,其中40例(28%)1〉0.20。发热患儿检查异型淋巴细胞1〉0.10共116例次,其中105例(90.5%)次出现在发热的第2~10天:8例无发热患儿异型淋巴细胞1〉0.10。误诊48例(33.6%)。合并症包括肝脏损害49例(34.5%),其中黄疸2例(1.4%);少量胸腔积液1例(0.7%);中枢神经系统损害、上呼吸道梗阻和中虔贫血均2例(1.4%):血小板减少、中性粒细胞减少以及青霉素过敏出皮疹各5例(3.5%)。结论深圳地区近年IM发生率有增多趋势,并且呈低年龄化。
Objective To analyze the clinical characteristics of infectious mononucleosis (IM) in children. Methods 143 of childhood IM were analyzed retrospectively from January,2001 to December, 2005. Results 82.5% of patients occurred under 6 years old, and 49% under 3 years old. The majority (132 cases,92.3% ) of presentations were fever, angina, lymphadenopathy and hepatosplenomegaly, fever was especially prevalent with a mean of (6.88± 3.26 ) days,81.1% of patients longer than 4 days, and 47.6% longer than 7days. Significant atypical lymphocytosis ( 90. 10 ) was present in 102 of patients(71.3% ) and atypical lymphocytosis in 40 cases(28% ) was higher than 0. 20. The Significant atypical cells in 90.5% ( 105 cases) of patients with fever was seen between 2 - 10 days from fever. The acute complications of IM included hepatitis 49 cases ( 34. 5 % ), central nervous system disorders 2 cases( 1.4% ) ,upper airway obstruction 2 cases( 1.4% ) ,midrange anemia 2 cases ( 1.4% ), thrombocytopenia 5 cases ( 3.5% ), neutrocytopenia 5 cases ( 3.5% ), and penicilline rash (3.5%). Conclusion The incidence rate of IM was increasing in Shenzhen recent years ,The age of childhood IM is younger than others domestic report in the past.
出处
《医药论坛杂志》
2006年第13期6-8,10,共4页
Journal of Medical Forum