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胸段硬膜外阻滞防治心肌梗死后心室重构探讨

Prevent or cure ventricular remodeling by thoracic epidural block after myocardial infarction
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摘要 Left ventricular remodeling is one of the major causes that results in heart failure after myocardial infarction. The therapeutic interventions that can slow or reverse the process are advisable. The mechanism of ventricular remodeling after myocardial infarction and the clinical experiences showed that thoracic epidural block was beneficial for cardiac angina, myocardial infarction, myocardiopathy or heart failure, and suggested that thoracic epidural block could prevent ventricular remodeling after myocardial infarction. Thoracic epidural block may therefore be a safe, economical and useful therapeutic strategy, besides medication or interventional therapy. Left ventricular remodeling is one of the major causes that results in heart failure after myocardial infarction. The therapeutic interventions that can slow or reverse the process are advisable. The mechanism of ventricular remodeling after myocardial infarction and the clinical experiences showed that thoracic epidural block was beneficial for cardiac angina, myocardial infarction, myocardiopathy or heart failure, and suggested that thoracic epidural block could prevent ventricular remodeling after myocardial infarction. Thoracic epidural block may therefore be a safe, economical and useful therapeutic strategy, besides medication or interventional therapy.
作者 石英 陈萍
出处 《国际麻醉学与复苏杂志》 CAS 2006年第4期239-241,共3页 International Journal of Anesthesiology and Resuscitation
关键词 左心室重构 心肌梗死 胸段硬膜外阻滞 防治 死后 心力衰竭 血运重建术 生活质量 生存率 用药物 ventricular remodeling thoracic epidural block myocardial infarction heart failure
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参考文献19

  • 1Udelson JE,Konstam MA.Relation between left ventricular remodeling and clinical outcomes in heart failure patients with left ventricular systolic dysfunction.J Card Fail,2002,8(6Suppl):465-471.
  • 2Harada K,Sugaya T,Murakami K,et al.Angiotensin Ⅱ type 1A receptor knockout mice display less left ventricular remodeling and improved survival after myocardial infarction.Circulation,1999,100(20):2093-2099.
  • 3Anand IS.Ventricular remodeling without cellular contractile dysfunction.J Card Fail,2002,8(6Suppl):401-408.
  • 4Villarreal FJ,Griffin M,Omens J,et al.Early short-term treatment with doxycycline modulates postinfarction left ventricular remodeling.Circulation,2003,108(12):1487-1492.
  • 5Hayashidani S,Tsutsui H,Ikeuchi M,et al.Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.Am J Physiol Heart Circ Physiol,2003,285(3):1229-1235.
  • 6Zee RY,Solomon SD,Ajani UA,et al.A prospective evaluation of the angiotensin-converting enzyme D/I polymorphism and left ventricular remodeling in the Healing and Early Afterload Reducing Therapy' study.Clin Genet,2002,61(1):21-25.
  • 7Sam F,Sawyer DB,Xie Z,et al.Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction.Circ Res,2001,89(4):351-356.
  • 8Blomberg S.Long-term home self-treatment with thoracic epidural anesthesia in patients with sever coronary artery disease.Anesth Analg,1994,79:413-421.
  • 9连祺周,傅世英.治疗顽固性心绞痛的新方法:高位硬膜外阻滞[J].心血管病学进展,2000,21(4):197-201. 被引量:5
  • 10高进,陈萍.硬膜外阻滞复合异丙酚对急性心肌梗死兔心肌损伤及细胞凋亡的影响[J].中华麻醉学杂志,2003,23(7):511-514. 被引量:5

二级参考文献38

  • 1饶曼人.药理学进展[M].北京:人民卫生出版社,1980.65.
  • 2师树英 卫生部继续医学教育委员会.心力衰竭的病理生理及治疗.国家级继续医学教育项目系列教材选编(心血管病分册),第1版[M].长春:长春出版社,1999.253.
  • 3Eugene Braunwald.Heart Disease.5th edition[M].北京:科学出版社,1999.1316-1331.
  • 4BraunwaldE.心脏病学[M].北京:科学出版社,1999.1404-1412.
  • 5Blomberg S, Curelaru I, Emanuelsson H, et al.Thoracic epidural anaesthesia in patient with unstable angina pectoris.Eur Heart J, 1989, 10:437-444.
  • 6Ravkilde H, Nissen H, Horder M, et al. Indepentent prognostic value of serum creatine kinase isoenzyme MB mass,cardiac troponin T and myosic light chain levels in suspected myocardial infarcfion.J Am Coll Cardiol,1995,25 : 574-481.
  • 7Hettes SW. To die or not to die:an overview of apoptosis and its role in disease.JAMA, 1998, 279: 300- 307.
  • 8Kajstura J, Cheng W, Reiss K, et al. Apoptesis and necrotic myocyte cell deaths are indepentent contributing variables of infarct size in rats. Lab Invest, 1996,74:86-107.
  • 9Long X,Boluyt MO,Hipolito ML,et al.p53 and the hypoxia-induced apoptosis of cultured neonatal rat cardiac myocytes.J Clin Invest, 1997,99:2635-2643.
  • 10Misao J, Hayakawa Y, Hono M, et al. Expression of Bcl-2 protein, an inbibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation, 1996,94 : 1506-12.

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