期刊文献+

血脂康对高血压患者颈动脉粥样硬化斑块的稳定和消退的临床研究 被引量:13

下载PDF
导出
摘要 目的评价血脂康对高血压病人颈动脉粥样硬化斑块(CP)的稳定和消退临床作用。方法应用高分辨率彩色超声仪,检查60岁以上高血压伴不同程度CP形成的患者88例,其中观察组60例,口服血脂康0.6 g每日两次。对照组30例。测定用药前后颈动脉粥样硬化斑块面积(CPA)和内膜中层厚度(IMT),肝功能,血脂。结果治疗组患者用药6个月后,其CPA和IMT,血脂与用药前有明显统计学差异(P<0.05)。TIA和UA发作次数较对照组明显减低(P<0.05)。结论血脂康有消退和稳定CP和缩小CPA和IMT,调脂以及减少缺血性心脑血管病事件发生和发展的作用。
作者 赵玉海
出处 《中国老年学杂志》 CAS CSCD 北大核心 2006年第8期1049-1050,共2页 Chinese Journal of Gerontology
  • 相关文献

参考文献7

二级参考文献52

  • 1李莹,王抒,陈文祥,徐晨,吕敏,李健斋.多中心临床试验研究中血脂测定室间质量控制[J].中华检验医学杂志,2004,27(10):656-659. 被引量:5
  • 2汪谦.现代医学实验方法[M].人民卫生出版社,1998.833.
  • 3[1]Scandinavian Simvastatin Survival Study Group. Randomise d trial of choles terol lowering in 4 444 patients with coronary heart disease: the Scandinavian Survival Study(4S)[J]. Lancet,1994,344:1383-1389.
  • 4[2]Sacks FM,Pfeffer MA,Moye LA,et al. The effect of pravastatin on coro nary events after myocardial infarction in patients with average cholesterol evels. Cholesterol and Recurrent Events Trial Ingestigarors[ J ]. N Engl J Med, 1996,335: 1001-1009.
  • 5[3]The Long-Term Intervention with Pravastatin in Ischemie Heart Disease (LIPID)Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of ini tial cholesterol Levels[J]. N Engl J Med,1998,339:1349-1357.
  • 6[4]Shepherd J,Cobbe SM,Ford 1,et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scot[and coronary prevention Study Group[J ]. N Engl J Med, 1995,333: 130l-1307.
  • 7[5]Downs JR,Clearfield M,Weis S,et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels Re sults of AFCAPS/Tex CAPS[J]. JAMA,1998,279:1615-1622.
  • 8[6]The lipid research clinics coronary primary prevention trial results. I reduc tion in incidence of coronary heart disease[J]. JAMA. 1984,251: 351-364
  • 9[7]NCEP(National Cholesterol Education Program). Guidelines of the second adult treatment panel( ATP I )[J]. JAMA,1993,267:3015-3023.
  • 10[8]The Post Coronary Artery Bypass Graft Trial Invesugators. The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low dose anticoagulation on obstructive changes in saphenous-vein coronary artery bypass grafts[J ]. N Engl J Med,1997,336:153-162.

共引文献317

同被引文献205

引证文献13

二级引证文献52

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部