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2型糖尿病患者颈动脉内膜中层厚度与细胞间黏附分子1、C反应蛋白的相关性 被引量：20

Association of intuna-media thickness of common carotid artery with intercellular adhesion molecule-1 and C-reactive protein in type 2 diabetic patients
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摘要 对55例2型糖尿病(DM)患者、25名正常对照者,分别用EHSA法、免疫散射比浊法测定血清可溶性细胞间黏附分子1(sICAM-1)、超敏C反应蛋白(hs-CRP)水平,用超声测定颈动脉内膜中层厚度(IMT)。结果提示sICAM-1、hs-CRP可能与2型DM患者颈动脉IMT的增厚有关。 The intima-media thickness （IMT） of common carotid artery was measured using B-mode ultrasonography in 55 patients with type 2 diabetes mellitus （DM） and 25 normal controls. The serum levels of soluble intercellular adhesion molecule-1 （sICAM-1） and high-sensitivity C-reactive protein （hs-CRP） were measured by ELISA and high-sensitivity particle enhanced immunonephelometry respectively. The results suggest that sICAM-1 and hs-CRP were risk factors of thickened IMT in type 2 DM.
作者 卢曙芳 沈建国 朱麒钱 官莉莉
机构地区 浙江大学医学院附属第一医院内分泌科 绍兴市第一医院
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2006年第4期358-359,共2页 Chinese Journal of Endocrinology and Metabolism
基金 浙江省教育厅科研基金资助(2005-1068)
关键词 2型糖尿病 内膜中层厚度 细胞间黏附分子1 C反应蛋白 Diabetes mellitus, type 2 Intima-media thickness Intercellular adhesion molecule-l C- reactive protein
分类号 R587.1 [医药卫生—内分泌]
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参考文献6

  • 1朱麒钱,尤巧英,李成江,李红,沈建国,斯徐伟,官莉莉,俞钟明,楼大均,金华伟.C反应蛋白与2型糖尿病大血管病变危险因素的相关性研究[J].中华内分泌代谢杂志,2005,21(4):320-321. 被引量：104
  • 2Haidari M, Javadl E, Sadeghi B, et al. Evaluation of C-reactive protein, a sensitive marker of inflammation, as a risk factor for stable coronary artery disease. Clin Biochem, 2001,33:309-315.
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二级参考文献13

  • 1王先令,陆菊明,潘长玉.不同糖耐量水平者血清C反应蛋白水平及阿卡波糖干预的影响[J].中华内分泌代谢杂志,2003,19(4):254-256. 被引量：43
  • 2吴伟华,张巾超,于江波,刘国良.2型糖尿病及合并大血管病变糖尿病患者C反应蛋白水平观察[J].中华内分泌代谢杂志,2003,19(4):257-259. 被引量：68
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  • 10Freeman DJ, Norrie J, Caslake MJ, et al. C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 2002,51:1596-1600.

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中华内分泌代谢杂志
2006年 第4期

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