摘要
转移性骨肿瘤被认为是癌相关性疼痛中最普遍的原因，由于癌性骨痛的机制不明，故其得不到很好的控制。近年来，股骨、肱骨、跟骨和胫骨癌痛动物模型的成功建立，深化了认识人类癌性骨痛的产生和发展机制，为进一步探索治疗此类痛症提供了努力方向，本文就癌性骨痛动物模型种类。病理机制及目前主要的治疗手段等方面所取得的进展进行了综述。
Metastatic bone tumors are thought to be the most common cause of cancer related pain, and cancer-induced bone pain cannot be well controlled because its underlying mechanisms are not clear. Recently, many animal models of cancer-induced bone pain have been successfully developed The advances in animal model kinds, pathological mechanism and medical therapy of cancer-induced bone pain were reviewed.
出处
《麻醉与监护论坛》
2006年第4期225-227,共3页
Forum of Anesthesia and Monitoring
基金
广州中医药大学科研创新基金（2005C050）资助
关键词
癌性骨痛
动物模型
病理机制
治疗
Cancer-induced bone pain
Animal model Pathological mechanism
Therapy
