摘要
研究了罗非鱼暴露于不同浓度溴氰菊酯后,组织中谷胱甘肽(GSH)的含量和谷胱甘肽-S-转移酶(GST)活性的动态变化.结果表明,以1.0,2.0,3.0,5.0,10.0μg/L浓度的溴氰菊酯处理罗非鱼25d,除了1.0μg/L浓度组罗非鱼体内GSH和GST与对照组无显著差异外,其余各浓度组的GSH和GST均发生了明显的变化,规律为先升高后降低,说明溴氰菊酯对罗非鱼体内的GSH和GST是先诱导后抑制,且肝脏的变化幅度比肌肉大.1.0μg/L以下的溴氰菊酯对罗非鱼没有生化毒性影响.罗非鱼组织中的GSH和GST可作为生物标志物来评价农药对鱼类的生化毒性.
The dynamic change of the content of Glutathione （GSH） and the activity of Glutathione-S-transferase （GST） in the tissue of tilipia after exposed to different concentration of deltamethrin was studied. Adopting of deltamethrin 1.0, 2.0, 3.0, 5.0, 10.0μg/L concentration to treat tilipia for 25d, except no marked difference of GSH and GST in the body of tilipia of 1.0μg/L concentration group compared with the contrast group, the GSH and GST of other remaining groups of different concentration all occurred obvious change, with the law of first raised and lowered afterward, indicating that it was first guiding and restarting afterward, deltamethrin on GSH and GST in the body of tilipia with the change range of liver was greater than that of muscle. The deltamethrin of below 1.0μg/L had no biochemical toxicity influence to tilipia. GSH and GST in the tilipia tissue could be used as a biomarker to appraise the biochemical toxicity of the pesticide to fishes.
出处
《中国环境科学》
EI
CAS
CSCD
北大核心
2006年第4期474-477,共4页
China Environmental Science
基金
国家科技基础条件平台项目(2004DEA70880-02-01-01)
