摘要
目的了解全市抗菌药品不良反应的发生和分布情况。为临床合理用药提供科学依据,发挥药品不良反应监测工作的指导作用。方法采用回顾性研究方法,对2004年1月～2005年6月全市药品不良反应监测中心收到的813例抗菌药品不良反应病例报告进行统计和分析。结果1723例不良反应病例报告中抗菌药品813例,占总数的47.19%,涉及7类、47个品种。其中头孢菌素类306例,占抗菌药品的37.64%;喹诺酮类221例,占27.18%;青霉素类116例,占14.27%。结论加强抗菌药品不良反应的监测,减少药品不良反应的重复发生,保障人民安全合理用药。
Objective By analyzing the occurrence and distribution of Adverse Drug Reaction（ADR） of antibacterial drugs in Zibo, to provide the scientific and exact information for rational drug in clinical practice and promote instructional function of ADR monitoring to ensure safe use of medicine in pubhc. Method 813 ADR reports of antibacterial drugs collected by Zibo Center for ADR Monitoring from January 2004 to June 2005 were analyzed using retrospective study method. Result Among all the ADR case reports, 813 case reports of antibacterial drugs including 7 classes and 47 kinds of drugs causing ADR, accounted for 47.18%. There were 306 case reports of cephalosporins （37.64%）, 221case repports of fluoroqinolones （27.18%）, 116 case reports of penicillcn （14.27%）. Conclusion ADR monitoring of antibacterial drugs should be strengthened, in order to avoid the occurrence of ADR again and ensure the safety and health for the people.
出处
《中国药物警戒》
2006年第5期286-288,共3页
Chinese Journal of Pharmacovigilance
关键词
药品不良反应
抗菌药品
统计分析
Adverse Drug Reaction
antibacterial drug
analysis
