期刊文献+

呼吸道病毒感染与支气管哮喘 被引量:1

Viral Respiratory Infections in Association with Bronchial Asthma
原文传递
导出
摘要 尽管呼吸道病毒感染导致气道炎症反应的机制尚不明确,但婴儿期严重的下呼吸道病毒感染可导致喘息反复发作,提示呼吸道病毒感染可能参与了哮喘的发病。流行病学资料显示,病毒感染是儿童及成年人哮喘恶化的主要原因之一,病毒感染可激活多种炎症细胞,改变气道平滑肌受体表达,通过调节神经免疫等机制导致哮喘恶化。抗病毒治疗或者针对气道炎症的治疗可减轻哮喘恶化的严重度及减少哮喘恶化的频率。
出处 《国际儿科学杂志》 2006年第5期327-329,共3页 International Journal of Pediatrics
  • 相关文献

参考文献15

  • 1Sigurs N,Gustafsson PM,Bjarnason R,et al.Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13[J].Am J Respir Crit Care Med,2005,171(2):137-141.
  • 2Stein RT,Sherrill D,Morgan WJ,et al.Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years[J].Lancet,1999,354(9178):541-545.
  • 3Henderson J,Hilliard TN,Sherriff A,et al.Hospitalization for RSV bronchiolitis before 12 months of age and subsequent asthma,atopy and wheeze:a longitudinal birth cohort study[J].Pediatr Allergy Immunol,2005,16(5):386-392.
  • 4Gern JE,Rosenthal LA,Sorkness RL,et al.Effects of viral respiratory infections on lung development and childhood asthma[J].J Allergy Clin Immunol,2005,115(4):668-674.
  • 5Sigurs N.Epidemiologic and clinical evidence of a respiratory syncytial virus-reactive airway disease link[J].Am J Respir Crit Care Med,2001,163(3 Pt 2):S2-6.
  • 6Eisenbarth SC,Piggott DA,Huleatt JW,et al.Lipopolysaccharide-enhanced,toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen[J].J Exp Med,2002,196(12):1645-1651.
  • 7Brimnes MK,Bonifaz L,Steinman RM,et al.Influenza virusinduced dendritic cell maturation is associated with the induction of strong T cell immunity to a coadministered,normally nonimmunogenic protein[J].J Exp Med,2003,198(1):133-144.
  • 8Jartti T,van den Hoogen B,Garofalo RP,et al.Metapneumovirus and acute wheezing in children[J].Lancet,2002,360(9343):1393-1394.
  • 9Rakes GP,Arruda E,Ingram JM,et al.Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care.IgE and eosinophil analyses[J].Am J Respir Crit Care Med,1999,159(3):785-790.
  • 10Zhao J,Takamura M,Yamaoka A,et al.Altered eosinophil levels as a result of viral infection in asthma exacerbation in childhood[J].Pediatr Allergy Immunol,2002,13(1):47-50.

同被引文献14

引证文献1

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部