期刊文献+

微透析技术在高血压性脑出血研究中的应用 被引量:1

下载PDF
导出
摘要 微透析技术是一种新型的在体生物化学采样技术。高血压性脑出血后由于缺血、缺氧,局部脑组织内发生一系列的神经化学改变,使用微透析技术能及时、有效地监测这些物质的变化,可靠地反映继发性脑缺血、脑损伤,为高血压性脑出血的研究、治疗提供了新方法。本文对微透析技术的原理、方法及其在高血压性脑出血研究方面的应用状况进行综述。
出处 《中国微侵袭神经外科杂志》 CAS 2006年第9期425-427,共3页 Chinese Journal of Minimally Invasive Neurosurgery
  • 相关文献

参考文献15

  • 1只达石,黄慧玲.微透析技术系统在神经科学中的应用[J].生物医学工程与临床,2005,9(1):56-60. 被引量:11
  • 2韩慧婉,舒鸿钧,刘国诠.微透析技术及其应用[J].化学通报,2000,63(12):52-56. 被引量:21
  • 3Qureshi AI, Ali Z, Suri MF, et al. Extracellular glutamate and other amino acids in experimental intracerebral hemorrhage: an in vivo microdialysis study [J]. Crit Care Med,2003; 31(5): 1482-1489.
  • 4Staub F, Gmf R, Gabel P, et al. Multiple interstitial substances measured by microdialysis in patients with subarachnoid hemorrhage [J]. Neurosurgery, 2000; 47(5): 1106-1116.
  • 5Sarmfzadeh AS, Haux D, Ludemann L, et al. Cerebral ischemia in aneurysmal subarachnoid hemorrhage: a correlative microdialysis-PET study [J]. Stroke, 2004; 35(3): 638-643.
  • 6Kett-White R, O'Connell MT, Hutchinson PJ. Extracellular amino acid changes in patients during reversible cerebral ischaemia [J]. Acta Neurochir (Wien), 2005; 95(Suppl): 83-88.
  • 7Frykholm P, Hillered L, Langstrom B, et al. Relationship between cerebral blood flow and oxygen metabolism, and extracellular glucose and lactate concentrations during middlecerebral artery occlusion and reperfusion: a microdialysis and positron emission tomography study in nonhuman primates [J]. J Neurosurg, 2005; 102(6): 1076-1084.
  • 8Ros J, Pecinska N, Alessandri B, et al. Lactate reduces glutamate-induced neurotoxicity in rat cortex [J]. J Neurosci Res, 2001; 66(5): 790-794.
  • 9Nilsson OG, Brandt L, Ungertedt U, et al. Bedside detection of brain ischemia using intracerebral microdialysis: subarachnoid hemorrhage and delayed ischemic deterioration[J]. Neurosurgery, 1999; 45(5): 1176-1185.
  • 10Melani A, Turchi D, Vannucchi MG, et al. ATP Extracellular concentrations are increased in the rat striatum during in vivo ischemia [J]. Neurochem Int, 2005; 47(6): 424-448.

二级参考文献33

  • 1舒鸿钧 韩慧婉 等.鼠脑微透析液中游离氨基酸的高效液相色谱分析[J].化学通报网络版,1999,:9900-9900.
  • 2Runnerstam M, yon Essen C, Nystr B. Extracellular glial fibrillary acidic protein and amino acids in brain regions of patients with subarachnoid hemorrhage-correlation with level of and site of bleeding[J].Neurol Res, 1997, 19(4):361-368.
  • 3Hutchinson PJ, Al-Rawi PG, O'Connell MT, et al. Biochemical changes related to hypoxia during cerebral aneurysm surgery: combined microdialysis and tissue oxygen monitoring:case report[J]. Neurosurgery, 2000, 46(1): 201-205.
  • 4Hutchinson PJ, AI-Rawi PG, O'Connell MT, et al. Monitoring of brain metabolism during aneurysm surgery using microdialysis and brain multiparameter sensors[J].Neurol Res, 1999,21(4) : 352-358.
  • 5Kanthan R, Shuaib A, Griebel R, et al. Intracerebral human microdialysis. In vivo study of an acute focal ischemic model of the human brain[J]. Stroke, 1995,26(5):870-873.
  • 6During MJ,Spencer DD. Adenosine:a potential mediator of seizure arrest and postictal refractoriness[J]. Ann Neurol, 1992,32(5):618-624.
  • 7Comford EM, Shamsa K, Zeitzer JM ,et al. Regional analyses of CNS microdialysate glucose and lactate in seizure patients[J]. Epilepsia,2002,43(11): 1360-1371.
  • 8O'Connell Mr, Tison F, Quinn NP, et al .Clinical drug monitoring by microdialysis:application to levodopa therapy in Parkinson's disease[J].Br J Clin Phannacol, 1996,42(6) : 765-769.
  • 9Bouw R, Ederoth P, l_andberg J, et al. Increased blood-brain barrier permeability of morphine in a patient with severe brain lesions as determined by microdialysis[J]. Acta Anaesthesiol Scand, 2001,45 (3):390-392.
  • 10Mindermann T, Zimmerli W, Gratzl O.Rifampin concentrations in various compartments of the human brain: a novel method for determining drug levels in the cerebral extracellular space[J]. Antimicrob Agents Chemother, 1998, 42(10): 2626-2629.

共引文献29

同被引文献20

  • 1张科平,张恒义,郑筱祥.微透析探针在体透析时间对氨基酸回收率的影响[J].浙江大学学报(医学版),2006,35(6):642-647. 被引量:5
  • 2Delgado JM, DeFeudis FV, Roth RH, et al. Dialytrode for long term intracerebral perfusion in awake monkeys [ J ]. Int Pharmacodyn Ther, 1972, 198(1) : 9 -21.
  • 3Tre ES, Patel C, Aghara S, et al. Optimization of perfusate pH to improve microdialysis recovery of lipophilic compounds [ J ]. J Pharmacol Toxicol Methods, 2012, 66(3): 276- 280.
  • 4Behrens PF, Langemann H, Strohschein R, et al. Extracellular glutamate and other metabolites in and around RG2 rat glioma: an intracerebral micmdialysis study [ J]. J Neurooncol, 2000, 47 ( 1 ) : 11 - 22.
  • 5Marcus HJ, Carpenter KLH, Price SJ, et al. In vivo assessment of high-grade glioma biochemistry using microdialysis: a study of energy- related molecules, growth factors and cytokines [ J ]. J Neurooncol, 2010, 97(1) : 11 -23.
  • 6Portnow J, Badie B, Liu X, et al. A pilot microdialysis study in brain tumor patients to assess changes in intracerebral cytokine levels after craniotomy and in response to treatment with a targeted anti-cancer agent [J]. J Neurooncol, 2014, 118(1) : 169 -177.
  • 7Roslin M, Henriksson R, Bergstrom P, et al. Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis [ J ]. J Neurooncol, 2003, 61 (2) : 151 - 160.
  • 8Melani A, De ME, Pinna G, et al. Adenosine extracellular levels in human brain gliomas: an intraoperative microdialysis study [ J ]. Neurosci Lett, 2003, 346 ( 1 - 2) : 93 - 96.
  • 9Grossman R, Tyler B, Rudek MA, et al. Microdialysis measurement of intratumoral temozolomide concentration after cediranib, a pan-VEGF receptor tyrosine kinase inhibitor, in a U87 glioma model [ J ]. Cancer Chemother Pharmacol, 2013, 72( 1 ): 93- 100.
  • 10Apparaju SK, Gudelsky GA, Desai PB. Pharmacokinetics of gemcitabine in tumor and non-tumor extracellular fluid of brain: an in vivo assessment in rats employing intracerebral microdialysis [ J ]. Cancer Chemother Pharmacol, 2008, 61 (2) : 223 -229.

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部