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体外膜氧合救治急性重症胰腺炎合并ARDS患者的临床研究 被引量:1

Clinical Study of Extracorporeal Membrane Oxygenation in the Treatment of Acute Respiratory Distress Syndrome Secondary to Severe Acute Pancreatitis
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摘要 目的:探讨体外膜氧合救治急性重症胰腺炎合并急性呼吸窘迫综合征(ARDS)患者的临床疗效。方法:使用美国百特公司BM-25床边血液净化仪,宁波亚泰公司FDMO-08中空纤维膜式氧合器,对10例急性重症胰腺炎(SAP)合并ARDS的患者进行治疗,观察治疗前后患者血氧分压、二氧化碳分压的变化。结果:10例患者中,6例好转,4例死亡。治疗前后患者的低氧血症有明显改善(P<0.05)。治疗前后动脉血二氧化碳分压无明显改变(P>0.05)。结论:体外膜氧合(ECMO)能迅速、有效提高急性重症胰腺炎合并ARDS患者的血氧浓度,提高SAP的抢救成功率。 Objective: To investigate the effect of extracorporeal membrane oxygenation in the treatment of acute respiratory distress syndrome secondary to severe acute pancreatitis (SAP). Methods:BM25 machine (Baxter, USA) and FDMO-08 hollow-fiber membrane oxygenator(Ningbo Yatai medical Instrument co. ltd) were used for the treatment of 10 patients with ARDS complicating SAP. Partial Pressure of Oxygen(PO2) and carbondioxide(PaCO2) were analyzed before and after treatment. Results:Clinical symptoms were singly improved in 6 out of 10 patient and 4 patients died. Hypoxernia was improved after treatment compared with that of before treatment (P〈 0.05), but there was no significant difference in PaCO2 ( P 〉 0.05 ). Conclusion: Extracorporeal membrane oxygenation can effectively and rapidly increase the blood oxygen concentration of patients with severe ARDS complicating acute pancreatitis.
出处 《中国中西医结合肾病杂志》 2006年第9期512-513,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
基金 杭州市卫生局科学基金资助项目(No.00A013)
关键词 体外膜氧合 急性重症胰腺炎 急性呼吸窘迫综合征 Extracorporeal membrane oxygenation Severe acute pancreatitis Acute respiratory distress syndrcrne
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