2Cowan PJ,Shinkel TA,Fisicaro N,et al.Targeting gene expression to endothelium in transgenic animals:a comparison of the human ICAM-2,PECAM-1 and endoglin promoters[J].Xenotransplantation,2003,10(3):223
3Fonsatti E,Del Vecchio L,Altomonte M,et al.Endoglin:an accessory component of the TGFβ-binding receptor complex with diagnostic,prognostic,and bioimmunotherapeutic potential in human malignancies[J].J Cell Physiol,2001,188:1
4Li.C,Hampson IN,Hampson L,et al.CD105 antagonizes the inhibitory signaling of transforming growth factor β1 on human vascular endothelial cells[J].FASEB J,2000,14:55
5Li DY,Sorensen LK,Brooke BS,et al.Defective angiogenesis in mice lacking endoglin[J].Science,1999,284:1534
8Luisa Diez-Marques,Rocio Ortega-Velazquez,Carmen Langa,et al.Expression of endoglin in human mesangial cells:modulation of extrascellular matrix synthesis[J].Biochimica et Biophysica Acta,2002,1587:36
9Luisa M,Botella,Francisco Sanz-Rodriguez,et al.Lumican is down-regulated in cells extressing endoglin.Evidence for an inverse correlationship between Endoglin and Lumican expression[J].Matrix Biology,2004,22:561
10Akagi K,Ikeda Y,Sumiyoshi Y,et al.Estimation of angiogenesis with anti-CD105 immunostaining in the process of colorectal cancer development[J].Surgery,2002,131(1):S109
4Sibai BM,Grids S,Hauth J; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.What we have learned about preeclampsia.Semin Perinatal,2003,27(3):239-246.
5Fonsatti E,Sigalotti L,Arslan P,et al.Emerging role of endoglin (CD105) as a marker of angiogenesis with clinical potential in human malignancies.Curr Cancer Drug Targets,2003,3(6):427-432.
6Toporaian M,Gros R,Kabir MG,et al.A role for endoglin in coupling eNOS activity and regulating vascular tone revealed in hereditary hemorrhagic telangiectasia.Circ Res,2005,96(6):684-692.
7Venkatesha S,Toporsian M,Lam C,et al.Soluble endoglin contributes to the pathogenesis of preeclampsia.Nat Med,2006,12(6):642-649.
8Chaiworapongsa T,Romero R,Kim YM,et al.Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia.J Matem Fetal Neonatal Med,2005,17(1):3-18.
9Hertig A,Berkane N,Lefevre G,et al.Maternal serum sFltl concentration is an early and reliable predictive marker of preeclampsia.Clin Chem,2004,50(9):1702-1703.
10Maynard SE,Min JY,Merchan J,et al.Excess placental soluble fins-like tyrosine kinase 1 (sFltl) may contribute to endothelial dysfunction,hypertension,and proteinuria in preeclampsia.J Clin Invest,2003,111(5):649-658.