摘要
目的:观察广东匙羹藤乙醇提取物(GIAE)对多种糖尿病小鼠动物模型的降血糖作用。方法:采用四氧嘧啶所致糖尿病小鼠模型、肾上腺素和葡萄糖引起的高血糖小鼠模型以及正常小鼠,在口服给药后,测定各模型小鼠的血糖水平。结果:GIAE对四氧嘧啶所致糖尿病小鼠有很好的治疗作用,对肾上腺素、葡萄糖引起的高血糖小鼠也有明显的降血糖作用,但对正常小鼠血糖无明显影响。结论:GIAE对多种糖尿病小鼠动物模型具有较好的降血糖作用。
Objective： To observe hypoglycemic effects of alcohol extracts from Gymnema inodorum （GIAE） on various animal models. Method： There are three models, including the diabetic animal model induced by alloxan, the hyperglycemic models induced by epinephrine and glucose, and the normal rats. After taken the drugs orally, the blood glucose levels of each model rat was deter- mined. Results： GIAE has better therapeutical action on diabetes mice induced by alloxan, and could significantly fall the blood glu- cose levels of hyperglycemic mice induced by epinephrine and glucose, but no significant effects on blood glucose levels of normal mice. Conclusion： GIAE has good hypoglycemic action on many kinds of diabetic mice models.
出处
《中医药导报》
2006年第9期67-68,共2页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
