期刊文献+

高敏C-反应蛋白和纤维蛋白原与老年冠心病的相关性研究 被引量:7

The relationship between high sensitive C-reactive protein and fibrinogen levels and coronary heart disease in elderly patients
下载PDF
导出
摘要 目的研究血清高敏C反应蛋白和纤维蛋白原(Fg)水平与冠心病之间的关系。方法对91例冠心病入院后12 h内、72例本院健康体检的老年人(对照组)空腹晨起静脉采血,检测血清高敏C反应蛋白和纤维蛋白原水平。结果冠心病组血清高敏C反应蛋白与健康对照组分别为(10.07±7.91)vs(4.57±1.29)mg/L,P<0.01;冠心病组血浆纤维蛋白原与健康对照组分别为(3.48±0.96)vs(2.65±0.38)g/L,P<0.01;冠心病血浆Fg与高敏C反应蛋白之间呈正相关,r=0.55。结论血清高敏C反应蛋白、纤维蛋白原水平增高,与老年冠心病有关。 Objective To study the relationship between hsCRP, Fg and coronary heart disease in elderly patients. Methods The venous blood samples were obtained from the 91 patients with CHD 12 hours after they were in hospital. The 72 healthy controls' blood samples were obtained in the morning after an overnight fasting. Then, the levels of hsCRP and Fg were determinateal. Results The Fg levels of CHD patients' were significantly different from those of the healthy controls (3.48 ± 0. 96 vs 2.65 ± 0. 38g/L,P 〈 0. 01 ) ;The hsCRP levels of CHD patients' were significantly different from those of the healthy controls ( 10.07 ± 7.91 vs 4.57 ± 1.29mg/L, P 〈 0. 01) ;The plasma Fg levels of CHD patients' correlated with the CRP levels,r = 0. 55. Conclusion The increased Fg and CRP levels are associated with CHD in elderly patients.
出处 《中国临床保健杂志》 CAS 2006年第5期425-426,共2页 Chinese Journal of Clinical Healthcare
关键词 冠状动脉疾病 C反应蛋白质 纤维蛋白原 Coronary disease C-Reactive protein Fibrinogen
  • 相关文献

参考文献7

  • 1[1]Chan DC,Watts GF,Barrett PH,et al.Effect of atorvastatin and fish oil on plasma high-sensitivity C-reactive protein concentrations in individuals with visceral obesity[J].Clin Chem,2002,48 (6):877-883.
  • 2[2]Nader R,Paul MR.high-sensitivity CRP:a novel and promising marker of coronary heart disease[J].Clinical Chemistry,2001,47(3):403-411.
  • 3[3]Abdelmouttaleb I,Danchin N,Ilardo C,et al.C-reactive protein and coronary artery disease:Additional evidence of the implication of an inflammatory process in acute coronary syndromes[J].Am Heart J,1999,137(2):346-351.
  • 4[4]Ridker PM,Hennekens CH,Buring JE,et al.C-reactive protein,and other markers of inflammation in the prediction of cardiovascular disease in women[J].N Engl J Med,2000,342(12):836-843.
  • 5[5]Herrick S,Blanc Brude O,Gray A,et al.Molecules in focus fibrinogen[J].Int J Biochem Cell Biol,1999,31 (7):741-746.
  • 6[6]Koenig W.Fibrinogen and coronary risk[J].Curr Cardiol Rep,1999,1 (2):112-118.
  • 7[7]Kofoed SC,Wittrup HH,Sillesen H,et al.Fibrinogen predicts ischemic stroke and advanced atherosclerosis but not echolucent,rupture-prone carotid plaques:The Copenhagen City Heart Study[J].Eur Heart J,2003,24(16):567-576.

同被引文献52

引证文献7

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部