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晨尿尿蛋白/尿渗透压比值测定的临床应用评价 被引量:11

Evaluation of protein-osmolality ratio of morning urine samples for quantitative assessment of proteinuria
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摘要 目的探讨晨尿尿蛋白/尿渗透压比值与24h尿蛋白定量的相关性。方法检测107例不同肾脏疾病患者的24h尿蛋白定量、晨尿尿蛋白/尿肌酐比值和尿蛋白/尿渗透压比值,并进行相关性分析。结果晨尿尿蛋白/尿渗透压比值与24h尿蛋白定量具有相关性(Y=1.14X+0.08;r=0.687,P<0.05);以尿蛋白/尿渗透压比值2.32作为临界值,本法的敏感性为94.7%,特异性为97.6%。结论晨尿尿蛋白/尿渗透压比值可替代24h尿蛋白定量广泛应用于临床。 Objective To evaluate the relationship between protein-osmolality ratio of morning urine and 24h urinary protein. Methods Urine samples of 107 patients with renal diseases were analyzed for 24h urinary protein,protein-osmolality ratio and protein-creatinine ratio. Results It was cornfirmed that there was a significantly positive correlation between the protein-osmolality ratio and the quantitation of 24 h urinary protein( Y= 1.14X +0.08 ; r= 0. 687, P〈0. 05 ). A protein-osmolality ratio of greater than 2.32 correlated with massive proteinuria(sensitivity 94.7 %, specificity 97.6% ). Conclusion Protein-osmolality ratio of morning urine samples can be used reliably to assess the degree of proteinuria.
出处 《国际检验医学杂志》 CAS 2006年第9期777-778,共2页 International Journal of Laboratory Medicine
关键词 尿蛋白 尿渗透压 尿肌酐 尿总蛋白 比值 Proteinuria urinary protein Creatinine osmolality ratio
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参考文献3

  • 1辛岗,王芳,王梅,焦莉莉,徐国宾,王海燕.点时间尿蛋白与尿肌酐比值检测的临床应用评价[J].中华肾脏病杂志,2005,21(5):247-250. 被引量:45
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  • 3National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis, 2002, 39(2 Suppl 1): S1-S266.

二级参考文献12

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