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2型糖尿病与冠心病患者心率震荡分析 被引量:8

Observation on the heart rate turbulence in daibetes mellitus and coronary heart disease patients.
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摘要 目的研究2型糖尿病与冠心病患者心率震荡(HRT)的变化及意义。方法选择有室性早搏的病人122例,分为2型糖尿病组、冠心病组和对照组,所有病人均行24h动态心电图监测,计算心率震荡的初始值(TO)、斜率(TS)。结果2型糖尿病组、冠心病组与对照组对比,均有TO升高、TS下降(P<0.05)。2型糖尿病组与冠心病组对比,TO、TS差异无显著性(P>0.05)。结论2型糖尿病与冠心病患者均有心率震荡的异常,存在心脏自主神经功能受损。HRT可作为2型糖尿病和冠心病临床上判断预后的重要心电指标。 Objective To study the alteration and difference of heart rate turbulence (HRT) in patients with type 2 diabetes mellitus (T2DM) and patients with coronary heart disease (CHD) . Methods 122 patients with ventricular premature beats were divided into T2DM group、CHD group and control group. All patients were examined with ambulatory electrocardiogram monitoring for twenty-four hours, and the turbulence onset (TO) and turbulence slope (TS) were analyzed. Results TO in the T2DM group and the CHD group was higher than that in the control group, and TS in the T2DM group and the CHD group was lower than that in the control group. TO and "IS had no significant difference between the T2DM group and the CHD group. Conclusion Function of cardiac autonomic nerve and HRT were abnormal in T2DM Patients and CHD patients, both TO and "IS had clinical prognostic value for sudden death in patients with T2DM or CHD.
出处 《中国热带医学》 CAS 2006年第9期1630-1631,共2页 China Tropical Medicine
基金 2006年度海南省教育厅高校科研指导性项目(Hj200630)
关键词 2型糖尿病 冠心痛 心率震荡 Type 2 diabetes mellitus Coronary heart disease Heart rate turbulence
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参考文献5

  • 1Schmidt G,Molik M,Barthel P,et al.Heart rate turbulence after ventricular premature beats as a predictor of mortality after acute myocardial infarction[J].Lancet,1999,353(7):1390~1396.
  • 2Morley-Davies A,Dargie HJ,Cobbe SM,et al.Heart rate turbulence:a novelholter derived measure and mortality in chronic heart failure[J].Eur Heart J,2000,21(2):408 ~ 416.
  • 3Chessa M,Butera G.Role of heart rate variability in the early diagnosis of diabetic autonomic neunopathy in children[J].Herz,2002,27(8):785.
  • 4Lucreziotti S,Gavazzi A,Scelsi L,et al.Five-minute recording of heart rate valiability in severe chronic heart failure:correlates with right ventricular function and prognostic implications[J].Am Heart J,2000,139(6):1088.
  • 5Hayana J,Yamada A,Mukai S,et al.Severity of coronary atheros-cl erosis is correlates with the respiratory component of heart rate variability[J].Am Heart J,1991,12(4):1070 ~ 1079.

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