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5-HT_3受体拮抗药研究概况 被引量:8

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摘要 恶性肿瘤化疗时胃肠道副反应引起的恶心、呕吐最为常见,大约占化疗病人的75%,这些不良反应降低了病人的生活质量,限制了用药疗程和剂量。近年来发现5-HT,受体拮抗药止吐疗效较为满意,并已发展为一类主要用于预防、治疗肿瘤的化疗和放疗诱发恶心、呕吐的新型药物。这类药物剂量小,止吐作用确切、毒副作用低,特别是没有多巴胺受体阻滞药常引起的严重锥体外系反应,被认为是“止吐疗法上的突破性的进步”。
作者 温悦 王丽婷
出处 《中国药师》 CAS 2006年第10期961-962,共2页 China Pharmacist
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参考文献15

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