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瑞芬太尼在20例镇痛肠镜检查中的应用

Application of remifentanil on 20 cases of analgesic enteroscopy
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摘要 [背景]探讨瑞芬太尼和丙泊酚应用于镇痛肠镜检查的可行性.[病例报告]选择ASAI,Ⅱ级需行肠镜检查的患者40例,随机分为瑞芬太尼组及芬太尼组.检查前给予瑞芬太尼组患者1μg/kg瑞芬太尼及1.0~1.5mg/kg丙泊酚静脉滴注,检查中给予瑞芬太尼0.05μg/(kg·min)及丙泊酚2mg/(kg·h)持续静脉滴注至检查结束;检查前芬太尼组患者给予芬太尼0.05mg/kg及丙泊酚1.0~1.5mg/kg静脉滴注,检查中给予丙泊酚2mg/(kg·h)持续静脉滴注,必要时追加滴注丙泊酚30~50mg.在肠镜检查过程中两组患者镇痛效果均较好,芬太尼组1例出现肢体扭动现象,追加静脉滴注丙泊酚后缓解;瑞芬太尼组1例出现肌肉僵硬及气短等症状,经面罩加压给氧后缓解.所有患者检查中生命体征均无明显变化,芬太尼组患者的清醒时间明显长于瑞芬太尼组.[讨论]瑞芬太尼应用于镇痛肠镜检查安全可行. BACKGROUND To study the feasibility of remifentanil and C parked phenol on analgesic enteroscopy. CASE REPORTS 40 cases of ASA Ⅰ , Ⅱ- enteroscope inspection patients were selected, and randomly divided into two groups, remifentanil group and fentanil group each 20 cases. Remifentanil group remifentanil 1 μg/kg, 60 seconds slow intravenous drug infusions C parked phenol 1.0- 1.5 mg/kg, intravenous drug infusions games with remifentanil 0.05 μg/(kg·min) plus C parked phenol 2 mg/(kg·h) continuous infusion to the end of surgery. Fentanil group controlled 0.05 mg C parked phenol 1.0-1.5 mg/kg intravenous drug infusions games with C parked phenol 2 mg/(kg·h) continued signs and, if necessary, additional C parked phenol 30-50 mg. After the results of the analgesic effect of the one sets of patients were very satisfied, with the emergence of two cases physically fentanil group phenomenon. Additional mitigation; remifentanil group C parked phenol after a one cases attracted serious and respiratory depression, with masks, pressurized pulmonary ease. There were no change in the lives of functional indicators in patients, games completed more sober time group obvious extension of the remifentanil obvious all the fentanil group. DISCUSSION Remifentanil phenol for outpatient analgesic enteroscope is safe and feasible.
机构地区 丹东市中心医院
出处 《延边大学医学学报》 CAS 2006年第3期197-199,共3页 Journal of Medical Science Yanbian University
关键词 肠镜检查 镇痛 瑞芬太尼 enteroscopy analgesia remifentanil
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参考文献3

  • 1Egan TD.Remifentanil pharmacokinetics and pharmacodnamics.A preliminary appraisal[J].Clin Pharmacokinet,1995,29:80.
  • 2吴新民,叶铁虎,岳云,许幸,易杰,田芳玲.国产注射用盐酸瑞芬太尼有效性和安全性的评价[J].中华麻醉学杂志,2003,23(4):245-248. 被引量:499
  • 3Milne Kenny GN,Schraag S.Propofol sparing effect of remifentanil using dosedloop anesthesia[J].Br J Anesth,2003,90:623.

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