摘要
电离辐射生物效应是辐射防护的生物学基础。辐射产生的有害健康效应分为两种类型①组织反应(也称确定性效应);②癌症及遗传效应(也称随机性效应)。为了辐射防护目的,ICRP将继续把辐射防护的实际体系建立在“线性无阈”剂量响应关系假设之上。在吸收剂量高至100mGy的剂量范围内(低LET或高LET),组织不会显现出这样的辐射敏感性,以致足以使临床相关功能损伤的阈剂量被超过。另外,还对非癌症疾病和宫内照射的辐射效应作了简单的介绍。
Biological effects of ionizing radiation are basis of radiation protection. The adverse health effects of radiation exposure may be grouped in two categories： ①tissue reactions（ also called deterministic effects）; ②cancer and heritable effects （also called stochastic effects）. For the purposes of radiation protection the practical system of radiological protection recommended by ICRP will continue to be based upon the ＂linear non-threshold＂ assumption at doses below around 100 mSv, and in the absorbed dose range up to around 100 mGy （low LET or high LET） no tissues are judged to show radiosensitivity that is sufficient to allow the dosethreshold for clinically relevant functional impairment to be exceeded. In addition, the non-cancer diseases and radiation effects in uterus exposure are also introduced briefly.
出处
《辐射防护通讯》
2006年第4期1-7,共7页
Radiation Protection Bulletin
关键词
随机性效应
组织反应
非癌症疾病
宫内照射
基因组不稳定性
旁效应
Stochastic effect Tissue reaction Non-cancer diseases Genomic instability Bystander effect In-uterus exposure
