期刊文献+

儿童肢体硬纤维瘤手术切除的疗效观察 被引量:4

Therapeutic effect of child limb desmoid tumor after operation
下载PDF
导出
摘要 [目的]探讨儿童肢体硬纤维瘤手术切除的复发率及有关因素,介绍综合治疗的最新进展;[方法]回顾性分析2001年以前手术切除8例儿童肢体硬纤维瘤的结果与复发率。8例儿童手术时平均年龄为8岁2个月,术后平均经过3a2个月(2a5个月~5a)的随访观察;肿瘤均位于儿童的肢体,4例位于臀部,3例位于大腿近端后侧并蔓延至胭窝下缘,1例位于上臂外侧三角肌的下缘。术前应用CT和MRI确定肿瘤部位与累积的范围,但未做活组织检查。8例均实现了边缘性切除,其中1例为外院部分切除的复发病例。[结果]本组8例手术切除的肿瘤组织均经病理证实为硬纤维瘤。术后平均经过3a2个月(2a5个月-5a)的随访观察,其中有4例肿瘤复发需要再次手术治疗。复发1次者2例,复发2次者1例,复发3次者1例。8例病人平均经历1.6次手术。复发率为69%,复发的间隔时间为6~10个月不等。1例因腓总神经位于肿瘤中央,切除肿瘤时导致腓总神经断裂性损伤;[结论]硬纤维瘤是一种侵袭性肿瘤,手术切除后复发率高达69%。采取手术切除和辅助性化疗或放疗是治疗该肿瘤的最新进展。
出处 《中国矫形外科杂志》 CAS CSCD 北大核心 2006年第19期1507-1508,共2页 Orthopedic Journal of China
  • 相关文献

参考文献9

  • 1Hosalkar HS,Fox EJ,Delaney T,et al.Desmoid tumors and current status of management[J].Orthop Clin North Am,2006,37 (1):53-63.
  • 2Schlemner M.Desmoid tumors and deep fibromatoses[J].Hematol Oncol Clin North Am,2005,19 (3):565-571.
  • 3Kuhnen C,Helwing M,Rabstein S,et al.Desmoid-type fibromatosis(aggressive fibromatosis)[J].Pathoioge,2005,26 (2):117-126.
  • 4Buitendijk S,van de Ven CP,Dumans TG,et al.Pediatric aggressive fibromatosis:a retrospective analysis of 13 patients and review of literature[J].Cancer,2005,104 (5):1090-1099.
  • 5Maseetall P,Robins JC,Williams DB,et al.Stabilization and regression of a recurrent desmoid tumor with the antiestrogen toremifene[J].Fertil Steril,2005,84 (2):509.
  • 6Seper L,Burger H,Vormoor J,et al.Agressive fibromatosis involving the mandible-case report and review of the literature[J].Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2005,99(2):254.
  • 7Wehl G,Rossler J,Otten JE,et al.Response ofprogressive fibromatosis to therapy with liposomal doxorubicin[J].Onkologie,2004,27 (6):552-556.
  • 8Mieke O,Seegenschmiedt MR.German cooperative group on radiotherapy for benign diseases.radiation therapy for aggressive fibromatosis(desmoidtumors):results of a national patterns of care study[J].Int J Radiat Oncol Biol Phys,2005,61 (3):882-891.
  • 9Mendenhall WM,Zlotecki RA,Morris CG,et al.Aggressive fibromatosis[J].Ami Clin Oncol,2005,28 (2):211-215.

同被引文献38

  • 1顾雅佳,彭卫军,王坚,王佩华.颈肩部纤维组织源性肿瘤的MR和CT诊断[J].中华放射学杂志,2005,39(12):1322-1326. 被引量:16
  • 2王珏,朱礼国,唐幕湘,张健.改良Masson三色染色法在胶原纤维中的应用[J].郧阳医学院学报,2006,25(1):44-44. 被引量:10
  • 3杨吉龙,王坚,周晓燕,侯英勇,朱雄增.韧带样型纤维瘤病中APC基因和β-catenin基因突变的研究[J].中华病理学杂志,2006,35(4):237-238. 被引量:3
  • 4Tse GM,Chen KF,Ahuga AT,et al.Fibromatosis of head and neck region[J].Otolaryngol Head Neck Surg,2001,125(5):516-519.
  • 5Thompson DH,Khan A,Gonzalez C,et al.Juvenile aggressive fibromatosis:report of three cases and review of the literature[J].Ear Nose Throat J,1991,70 (7):462-468.
  • 6Saito T,Oda Y,Kawaguchi K,et al.Possible association between higher betacatenir mRNA expression and mutated betacatmin in sporadic desmcin tumors:real-time semiquantitative assay by TaqMan polymerase chain reaction[J].Lab Invest,2002,82(1):97-103.
  • 7Weber BP,Kempf HG,Lwnz M,et al.Diagnosis and therapy of aggressive fibromatosis (extra-sbdominal desmoid)in the head and neck areap[J].Laryngorhinootologie,1991,70(7):367-374.
  • 8Tse GM,Chen KF,Ahuga AT,et al.Fibromatosis of head and neck region[J].Otolaryngol Head Neck Surg,2001,125(5)516-519.
  • 9Yoshida S,Kimura H,Iwai N,et al.A surgical case of aggressive fibromatosis[J].Nippon Kyobu Geka Gakkai Zasshi,1997,45(12):2016-2020.
  • 10Fujimoto Y,Hidai K.Aggressive fibromatosis in the neck.a case treated effectively by testolactone with a long follow-up study[J].Jpn J Surg,1990,20(4):453-457.

引证文献4

二级引证文献39

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部