摘要
目的:观察脑脉安颗粒对急性脑梗死患者血浆同型半胱氨酸水平的影响。方法:选取符合标准的急性脑梗死患者60例,随机分为脑脉安颗粒(每次9g,每日2次)加西医基础治疗组(n=30)和单纯西医基础治疗对照组(n=30),治疗前和治疗两周后分别检测HCY、V it-B12和THF,并与健康老年人对照。结果:脑梗死组治疗前与健康组比较,脑梗死组血浆HCY水平显著高于健康组、血清THF和V it-B12水平显著低于健康组(P<0.01);两组患者治疗后较治疗前血浆HCY水平显著降低、血清THF和V it-B12水平均显著升高(P<0.01);治疗后治疗组较对照组血浆HCY水平显著降低、血清THF和V it-B12水平均升高明显(P<0.05)。结论:脑脉安颗粒对血浆HCY水平有明显降低作用,其部分机制与脑脉安颗粒能显著升高血中THF和V it-B12水平。
Objective： To observe the effect of Naomaian Granule on the plasma Homocysteine（HCY） in the sufferer of acute cerebral infarction. Method：60 cases of acute cerebral medicine （n = 30） and only treatment by west medicine （ n = 30 ）. Meanwhile, 25 health cases control group. Pre - treatment and after treatment, Homocysteine（ HCY）, Vitamin - B12 （ Vit - B12 ） and Tetrahydrofo- late（THF） in the plasma or serum were examined. Results： Before treatment, the level of HCY in the group of acute cerebral infarction was higher than health group, at the same time, the level of of THF and VitB12 increased significantly. After treatment, the level of HCY was decreased and THF and Vit - B12 were increased. Conclusion： The level of HCY could be decreased by Naomaian Granule. This effect can be related to its influence on the THF and Vit - B12.
出处
《辽宁中医杂志》
CAS
北大核心
2006年第9期1198-1199,共2页
Liaoning Journal of Traditional Chinese Medicine
