摘要
目的建立诊断轻微肝性脑病(MHE)的有效数字连接试验(NCT)-A、数码符号试验(DST)等简易智能测试的正常范围。方法选择至少接受9年以上教育的健康志愿者160名,按年龄分为＜35岁组、35～44岁组、45～54岁组和55～64岁组,全部接受NCT-A、DST等简易智能测试,建立与年龄相关的正常人群均值及标准差,以均数±2标准差作为MHE的诊断标准,用于检测106例肝硬化患者。结果160名健康志愿者的NCT-A在＜35岁组、35～44岁组、45～54岁组和55～64岁组分别为(25．1±4．6)s、(32．1±6．8)s、(38．6±7．1)s和(49．3±6．3)s,DST分数分别为49．9±4．7、44．6±4．8、38．5±5．0和35．4±4．7。106例肝硬化患者以此为标准,诊断出MHE患者31例(29．2%)。结论NCT-A、DST等简易智能测试可用于MHE的诊断,并应建立与年龄相关的正常范围。
Objective To establish the normal parameters of psychometric measures such as the number connection tests A（NCT-A） and digit symbol tests （DST） in assessment of minimal hepatic en cephalopathy（MHE）. Methods One hundred and sixty healthy volunteers （aged 25 to 64 years; educa tional level 〉 9 years） were divided into 〈 35 ys, 35-44 ys, 45-54 ys and 55-64 ys groups. All of the healthy volunteers were assessed with NCT-A and DST to establish the normal value of age-related parameters, which can be used for diagnosis of MHE in patients with liver cirrhosis. Two standard devi ation of the normal mean was used as a diagnostic criterion for MHE. One hundred and six cirrhotic patients were assessed with these parameters. Results The parameters of NCT-A were （25. 1 ± 4.6） sec in〈35 ysgroup, （32.1±6.8） sec in 35-44 ys group, （38.6±7. 1） sec in45-54 ys group or （49.3± 6. 3）sec in 55-64 ys group. The scores of DST were 49. 9 ± 4. 7 in 〈 35 ys group, 44. 6 ±4.8 in 35-44 ys group, 38.5 ± 5.0 in 45-54 ys group or 35.4 ± 4.7 in 55-64 ys group. Thirty one out of 106 cirrhotic patients were diagnosed as MHE based on these parameters. Conclusion The NCT- A and DST are psychometric assessments for diagnosis of MHE. Age-based normal paramerters of NCT A and DST are needed to be established.
出处
《中华消化杂志》
CAS
CSCD
北大核心
2006年第9期606-609,共4页
Chinese Journal of Digestion
基金
上海市重点学科建设资助项目(Y0205)
关键词
肝硬化
轻微肝性脑病
数字连接试验
数码符号试验
Liver cirrhosis
Minimal hepatic encephalopathy
Number connection test
Digit symbol test
