摘要
目的了解安徽省葡萄球菌属细菌的耐药情况。方法随机抽取安徽省细菌耐药监控网成员中的13所医院,2004年9月收集的葡萄球菌属细菌,采用琼脂平皿稀释法,对12种抗菌药物进行MIC测定。结果金黄色葡萄球菌及凝固酶阴性葡萄球菌对青霉素的耐药率最高,分别是100.0%和92.9%;对大环内酯类抗菌药物的耐药率亦约90.0%,对万古霉素均敏感。结论安徽省各级医院中均存在着不同程度的葡萄球菌属细菌耐药情况,应加强细菌的耐药性监控,并强调抗菌药物的合理应用。
OBjECTIVE To obtain the statistics of the resistance of Staphylococcus spp to 12 antibacterial agents. METHODS The clinical non-repeated isolates of Staphylococcus aureus and coagulase negative Staphylococcus （CNS） were collected in September 2004 in 13 hospitals of Anhui Province. According to National Committee for Clinical Laboratory Standards（NCCLS） of America（2004）, agar dilution method was performed to determine the MICs of 12 antimicrobial agents against the isolates. RESULTS All S. aureus and 92.9 M of CNS were resistant to penicillin respectively. Multi-resistance to antibiotics such as macrolides, and fluoroquinolones were found in these strains, and all the isolates of Staphylococcus spp were susceptible to vancomycin. CONCLUSIONS Staphylococcus spp exhibit some degrees of resistance to antimicrobial agents in Anhui Province. Therefore, the drug resistance of surveillance must be imposed, and we must emphasize on reasonable option of antimicrobial agents in clinical therapy in our area.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2006年第10期1165-1166,1186,共3页
Chinese Journal of Nosocomiology
基金
国家自然科学基金项目(30571654)
关键词
葡萄球菌属
耐药性
MIC
Staphylococcus spp
Resistance
Minimal inhibitory concentration
