期刊文献+

不稳定性心绞痛患者hs-CRP水平与冠心病危险因素的关系及其与预后的相关性实验观察

Experimental Observation of Prognostic Relativity of hs-CRP Levels in Patients with Unsteadiness Angina and Coronary Heart Disease Risk Factors
下载PDF
导出
摘要 探讨不稳定性心绞痛(UA)患者血浆高敏C-反应蛋白(hs—CRP)水平与冠心病危险因素的关系及其对临床预后预测的价值。对483例入院UA患者进行了血浆hs—CRP检测及其他相关检查,并对其中472例进行1~30(25.6±5.6)个月的随访,以观察其不良心血管事件的发生率。结果发现,472例UA患者中hs—CRP增高者出现高血压、血脂异常、2型糖尿病(2DM)等血管事件的比率显著较高,hs—CRP增高者中吸烟者比例较大。作者认为入院时hs—CRP水平增高是UA患者心血管事件增高的危险预测因子之一。 To study relationship of changes of plasma hs-CRP level in patient with unsteadiness angina(UA) and coronary heart disease rick factors in prognosis, plasma hs-CRP levels were measured in 483 patients with UA. The incidence of poor cardiovascular vessels was followed- up for 1 to 30(25.6-+-5.6) months. Results showed that there was a relatively high proportion of cardiovascular events in subjects suffering from hepertention, lipoprotein abnormity, 2-type diabetes meuitus or smokers of 472 UA patients with increasing hs-CRP. This paper discribed that increasing of plasma hs-CRP levels in the time of admission was a risk prognostic factor for high incidence of cardiovascular events in patients with UA.
出处 《标记免疫分析与临床》 CAS 2006年第3期135-136,共2页 Labeled Immunoassays and Clinical Medicine
关键词 冠状动脉疾病 不稳定性心绞痛 C-反应蛋白质 Coronary artery disease Unsteadiness angina Hs-CRP
  • 相关文献

参考文献5

二级参考文献28

  • 1Laaksonen DE, Niskanen L, Punnonen K, et al. Sex hormones, inflammation and the metabolic syndrome: a population-based study. Eur J Endocrinol, 2003, 149: 601-608.
  • 2Pradhan AD, Cook NR, Buring JE, et al. C-reactive protein is independently associated with fasting insulin in nondiabetic women.Arterioscler Thromb Vasc Biol, 2003, 23: 650-655.
  • 3Freeman DJ, Norrie J, Caslake MJ, et al. C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes, 2002, 51: 1596-1600.
  • 4Ridker PM, Rifai N, Rose L, et al. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med, 2002, 347: 1557-1565.
  • 5Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA,2001, 285: 2486-2497.
  • 6Stuveling EM, Bakker SJ, Hillege HL, et al. C-reactive protein modifies the relationship between blood pressure and microalbuminuria. Hypertension, 2004, 43:791-796.
  • 7Devaraj S, Xu DY, Jialal I. C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis. Circulation, 2003, 107: 398-404.
  • 8Devereux RB, Alonso DR, Lutas EM, et al.Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol, 1986, 57: 450-458.
  • 9Tan CE, Chew SK, Ma S, et al. Can we apply the National Cholesterol Education Program Adult Treatment Panel definition of the metabolic syndrome to Asians? Diabetes Care, 2004, 27:1182-1186.
  • 10Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation, 2003,107: 363-369.

共引文献72

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部