期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

胎盘生长因子及其受体在妇产科领域的研究进展 被引量：2

Study on Placental Growth Factor and its Receptor(VEGFR-1/Flt-1)in Obstetrical and Gynecological Field
下载PDF
导出
摘要 胎盘生长因子(PLGF)是血管内皮生长因子(VEGF)家族成员之一。它通过与其受体VEGFR-1(Flt-1)结合发挥生物学作用,促进新生血管形成,参与了肿瘤,炎症等病理生理过程。研究表明PLGF及其受体在妊娠并发症、子宫内膜异位症和肿瘤中起着重要作用。 Placental growth factor （PLGF）is a member of vascular endothelial growth factor family. It can play its biological effects in promoting neovascularization and taking part in the pathophysical course of tumor, inflammation and so on by binding with its receptor VEGFR- 1 （ Flt- 1 ）. Studies indicate that placental growth factor and its receptor play key roles in the complication of pregnancy, endometfiosis and gynecological tumor.
作者 王竹辉 何福仙
机构地区 荆州市第二人民医院 华中科技大学同济医学院
出处 《医学综述》 2006年第19期1163-1165,共3页 Medical Recapitulate
关键词 胎盘生长因子 妊娠并发症 子宫内膜异位症 Placental growth factor Complication of pregnancy Endometriosis
分类号 R714.25 [医药卫生—妇产科学]
  • 相关文献

参考文献21

  • 1De Falco S,Gigante B,Persico MG.Stucture and function of placental growth factor[J].Trends Cardiovasc Med,2002,12(6):241-246.
  • 2Tjwa M,luttun A,Autiero M,et al.VEGF and PLGF two pleiotropic growth factors with distinct roles in development and hemostasis[J].Cell Tissue Res,2003,314(1):5-14.
  • 3Shibata E,Rajakumar A,Powers RW,et al.Soluble fms-like tyrosine kinse 1 is increased in preeclampsia but not in normotensive pregnancies with small-for-gestational-age neonates:relationship to circulating placental groth factor[J].J Clin Endocrinol Metab,2005,90(8):4895-4903.
  • 4Cho GJ,Rob GS,Kim HJ,et al.Differential expression of placenta growth factors and their receptors in the normal and pregnancy-induced hgrentensive human placentas[J].J Korean Med Sci,2003,18(3):402-408.
  • 5Torry Ds,Hinrichs M,Torry RJ.Determinants and placental vascularity[J].Am J Reprod Immunol,2004,51(4):257-260.
  • 6Loukovara M,Leinonen P,Teramo K,et al.Concentration of cord serum placental growth factor in normal and diabetic pregnancies[J].BJOG,2005,112(1):75-79.
  • 7Krauss T,Pauer HV,Angustin HG.Prospective analysis of placenta growth factor (PLGF) concentrations in th plasma of woman with normal pregnancy and pregnancies conpliented by preeclampsia[J].Hypertens Pregnancy,2004,23(1):101-111.
  • 8Bujoid E,Romero R,Chaiworapongsa T,et al.Evidence supporting that the excess of the sYEGFR -1 concentration in maternal plasma in preeclampsia has a uterine origin[J].J Matern Fetal Neonatal Med,2005,18(1):9-16.
  • 9Maynard SE,Min JY,Merchan J,et al.Excess placental soluble fmslike tyrosin kinase 1 (sFlt 1) may contribute to endothelial dysfun ction,hypertension,and proteinuria in preeclampsia[J].J Clin Invest,2003,111(5):649-658.
  • 10Levine RJ,Thadhani R,Qian C,et al.Urinary placental growth factor and risk of preaclampsia[J].JAMA,2005,293 (1):77-85.

同被引文献24

  • 1范春明,罗希,温放.CA125、CA19-9联合检测在卵巢上皮癌和子宫内膜异位症中的临床价值[J].中国医科大学学报,2009,38(5):376-378. 被引量：9
  • 2景栋林,邓日烈,王晔,徐跟学,张文华.梅花猪的繁殖性能分析[J].中国畜牧杂志,2007,43(5):57-58. 被引量：3
  • 3苑春莉,王医术,盛辉,李荷莲,马宁,王筱璐,曾晓娟.胰岛素样生长因子Ⅰ及其受体在子宫内膜异位症中的表达[J].吉林大学学报（医学版）,2007,33(3):567-569. 被引量：5
  • 4Christianson W T. Stillbirths, mummies, abortions, and early embryonic death [ J ]. Vet Clin North Am Food Animal Practice, 1992, 8(3): 623-623.
  • 5Lucia J T, Corre^a M N, Deschamps J C, et al. Risk factors for stillbirth in two swine farms in the south of Brazil [ J ]. Preventive Veterinary Medicine, 2002, 53: 285-292.
  • 6Sanders L M, Bilkei G. Urogenital diseases and their effect on reproductive performance in high-parity sows [ J ]. Tijdschr Diergeneeskd, 2004, 129(4) : 108-112.
  • 7Borges V F, Bernardi M L, Bortolozzo F P, et al. Risk factors for stillbirth and foetal mummification in four Brazilian swine herds [ J ]. Preventive Veterinary Medicine, 2005, 70 : 165-176.
  • 8Ahmed A, Dunk C, Ahmad S, et al. Regulation of placental vascular end othelial growth factor (VEGF) and placental growth factor (PLGF) and soluble Fit-1 by oxygen-a review [ J ]. Placenta, 2000, 21 (SupplA) : S16-24.
  • 9Petersen M, Larsen T, Nielsen H J. Angiogenic proteins: possible Markers of physiopathological processes during fetal development [ J ]. Vgcskrlacgcr, 2003, 165 (32) : 3082-3087.
  • 10Szukiewicz D, Szewczyk G, Watroba M, et al. Isolated placental vessel response to vascular endothelial growth factor and placenta growth factor in normal and growth-restricted pregnancy [ J ]. Gynecol Obstet In-vest, 2005, 59(2) : 102-107.

引证文献2

二级引证文献8

医学综述
2006年 第19期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部