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危重症监护室呼吸机相关性肺炎高危因素分析及预防 被引量:13

Analysis and prevention of high risk factors of ventilator-associated pneumonia in ICU
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摘要 目的探讨呼吸机相关性肺炎(VAP)的发病率、病死率和危险因素,为防治VAP提供科学依据。方法回顾性分析本院ICU机械通气下发生VAP的患者的临床资料和痰培养结果,并提出相应措施。结果VAP发生率46%,死亡19例(53%),相关危险因素:年龄>60岁、昏迷、各种侵入性操作、气管切开、慢性阻塞性肺疾病、机械通气>3 d(P均<0.05)。主要病原体为绿脓杆菌、大肠埃希菌、肺炎克雷伯菌、阴沟肠杆菌和真菌。结论延长机械通气时间增加了VAP发生率,且对预后造成不良影响,应尽可能早脱机。 Objective It is to study mobidity, mortality and risk factors of ventilator associated pneumonia (VAP) and to provide scientific basis for prevention and cure of VAP. Methods The clinical data and sputum culture results of VAP patients in ICU were analyzed retrospectively, and the treatment strategies were introduced. Results The mobidity of VAP was 46 % and the mortality was 53 % (19 cases). The related risk factors were age over 60 years, coma, all kinds of virulence operation, tracheotomy, chronic obstructive pulmonary diseases and mechanical ventilation over three days (P 〈 0.05). The main bacteria were Aeruginosus Bacillus, Escherichia coli, Pneumonia klebsiella, Enterobacter cloacae and fungus. Conclusion Lengthening mechanical ventilation time has increased VAP mobidity and has caused infaust affection on prognosis, so the off line should be completed early.
出处 《现代中西医结合杂志》 CAS 2006年第21期2892-2893,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词 机械通气 危险因素 呼吸机相关性肺炎 mechanical ventilation risk factors ventilator associated pneumonia
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