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血清瘦素水平检测在糖尿病视网膜病变中的意义 被引量:1

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摘要 目的探讨糖尿病视网膜病变患者血清瘦素水平变化的意义。方法采用放射免疫分析法,用国产及进口试剂分别检测35例健康体检人员及105例各类糖尿病患者血清瘦素、胰岛素水平。血糖浓度采用葡萄糖氧化酶法测定。分析瘦素水平与糖尿病视网膜病变的相关性。结果对照组、无视网膜病变(NODR)组、非增殖性糖尿病视网膜病变(NPDR)组及增殖性糖尿病视网膜病变(PDR)组血清瘦素浓度分别为6.23±1.73μg/L,7.63±2.36μg/L,10.96±1.23μg/L和18.3±2.41μg/L,经协方差分析排除体重指数的影响,PDR组血清瘦素浓度明显高于NPDR组(P<0.05)、NODR组(P<0.05)及对照组(P<0.05);NPDR组血清瘦素浓度高于NODR组(P<0.05)及对照组(P<0.05)。结论糖尿病视网膜病变患者血清瘦素浓度升高,且增高的幅度与病情的严重程度正相关。
出处 《福建医药杂志》 CAS 2006年第5期34-36,共3页 Fujian Medical Journal
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  • 1Bouloumine A,Drexler HC,Lafontan M,et al.Leptin,the product of obgene,promotes angiogenesis.Circ Res.1998,83(10):1059-1066.
  • 2Sierra-Honigmann MR,Nath AK,Murakami C,et al.Biological action of leptin as an angiogenic factor.Science,1998,281(5383):1683-1686.
  • 3Chan JL,Bluher S,Yiannakouris N,et al.Regulation of circulating soluble leptin receptor levels by gender,adiposity,sexsteroids,and leptin observational and interventional studies in human.Diabetes,2002,51 (7):2105-2112.
  • 4Gokhan U,Metin O,Zeki B,et al.Is leptin associated with diabetic retinopathy.Diab Care,2000,23 (3):371-376. Gokhan U,Metin O,Zeki B,et al.Is leptin associated with diabetic retinopathy.Diab Care,2000,23 (3):371-376. [5]Gariano RF,Nath AK,Amico DJ,et al.Elevation of vitreous leptin in diabetic retinopathy and retinal detachment.Invest Ophthalmol Vis Sci,2000,41 (11):3576-3581.
  • 5Gokhan U,Metin O,Zeki B,et al.Is leptin associated with diabetic retinopathy.Diab Care,2000,23 (3):371-376. [5]Gariano RF,Nath AK,Amico DJ,et al.Elevation of vitreous leptin in diabetic retinopathy and retinal detachment.Invest Ophthalmol Vis Sci,2000,41 (11):3576-3581.
  • 6赵跃斌,李兴.HGF和瘦素在糖尿病视网膜病变中的作用[J].国外医学(眼科学分册),2003,27(6):344-346. 被引量:1
  • 7Ckaya G,Ozata M,Bauraktar Z,et al.Is leptin associated with diabetic retinopathy.Diabetes Care,2000,23 (3):371-376.

二级参考文献10

  • 1Gariano RF et al. Investigative Ophthalmology . 2000
  • 2Uckaya G et al. Diabetes Care . 2000
  • 3Grierson I et al. Progress in Retinal and Eye Research . 2000
  • 4Funatsu T et al. Journal of Thoracic and Cardiovascular Surgery . 2002
  • 5Nishimura M et al. The Journal of Clinical Endocrinology . 1999
  • 6Katsura Y et al. Diabetes Care . 1998
  • 7Nishimura M et al. Rinsho Byori . 1998
  • 8Chavakis E et al. Arteriosclerosis and Thrombosis . 2002
  • 9Nakagami H et al. Diabetes . 2002
  • 10Cai W et al. Investigative Ophthalmology . 2000

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