摘要
目的:探讨慢性肾炎患者精液质量及其影响机制。方法:对35例不同阶段的慢性肾炎及20例健康志愿者精液常规检验结果进行统计分析。结果:慢性肾炎患者的精液主要参数(精子活动力、存活率)明显下降,形态镜检异常,与对照组相比较差异有显著性统计意义(P<0·05),慢性肾炎患者的血清尿素氮、肌酐含量与精液常规参数值呈负相关(r=-0·05,P<0·01)。结论:慢性肾炎患者代谢毒素物质可能使精子细胞受损、存活率、活动力下降,并且导致精子畸形率增加。
Objective： To investigate the effect of semen quality and morphology change in chronic nephritis. Methods： Semen routine analysis was referenced to WHO standard （ the forth edition of 2001 ）. 35 cases of the chronic nephritis patients in differont stage and 20 cases of health volunteers accepted routine semen qualitative test. Results ： The main parameters of semen （the seminal active and its survival rate） declined and its morphlogy were abnormal in the chronic nephritis group than the control grovp, which showed significant difference （ P 〈 0.05 ）. Conclusion： The toxin metabolite of chronic nephritis patients can lead to seminal cell division, the seminal survival rate and active declining, and the seminal malformation rate increasing and its morphology changing.
出处
《中国计划生育学杂志》
北大核心
2006年第10期619-620,共2页
Chinese Journal of Family Planning
关键词
慢性肾炎
精液质量
尿素氮
肌酐
Chronic nephritis Semen quality Urea nitrogen Creatinine
