摘要
目的探讨实时超声造影在子宫肌瘤和腺肌瘤中的灌注特征及其鉴别诊断价值。方法选择64例子宫肌瘤和29例腺肌瘤患者进行实时超声造影检查,全部病例均经手术或超声引导下穿刺活检证实。造影剂选用SonoVue,剂量为2.4 ml,以团注方式由肘部浅静脉注入。绘制时间-强度曲线,分析各病灶的造影剂灌注特征。结果64例子宫肌瘤中有62例表现为瘤体周边首先增强,形成一个特征性的半环状增强影,1例表现为周边和瘤体内部同时增强,1例表现为瘤体中心首先增强;达峰后60例瘤体与周围正常组织有明显边界。29例子宫腺肌瘤均表现为瘤体内部首先增强,出现散在短线状的增强影,继之整个瘤体迅速增强;达峰后,所有瘤体强度均与周围正常组织相似,无明显边界。造影后子宫肌瘤和腺肌瘤峰值强度、始增时间、达峰时间以及增强时间各参数比较差异无统计学意义。结论子宫肌瘤和腺肌瘤实时超声造影不同的灌注模式和特征对鉴别诊断有重要意义。
Objective To assess the characteristics and the value of real time contrast enhanced ultrasound in the differential diagnosis between uterine leiomyoma and endometrioma. Methods Sixty-four patients with uterine leiomyoma and 29 with endometrioma were enrolled in the study and all the patients were confirmed by operation or ultrasound-guided needle puncture biopsy. New contrast agent SonoVue was iniected intravenously as a bolus in 2.4 ml and real time contrast enhanced ultrasound was performed to observe the enhanced pattern and characteristics. Results After the administration of SonoVue, 62 patients with uterine leiomyoma showed peripherial globular enhancement pattern and centripetal filling immediately. There was a clear border between the tumor and the adjacent uterine parenchyma in 60 patients. All the 29 patients with endometrioma showed intratumor enhancement pattern and remained isoechoic with respect to the surrounding tissue. There was no clear border between the tumor and the adiacent uterine parenchyma. There was no significance comparing the parameters of peak intensity, initiation time of enhancement, time of reaching peak intensity and enhancement duration between two groups. Conclusions Real time contrast enhanced ultrasound shows different enhancement pattern and characteristics of uterine leiomyoma and endometrioma, it should be as an important tool for differential diagnosis.
出处
《中华超声影像学杂志》
CSCD
2006年第10期770-772,共3页
Chinese Journal of Ultrasonography
关键词
超声检查
造影剂
子宫肿瘤
平滑肌瘤
腺肌瘤
Ultrasonography
Contrast media
Uterine neoplasms
Leiomyoma
Adenomyoma
