摘要
目的建立阿托伐他汀钙分散片溶出度的测定方法。方法以水为溶出介质,采用浆法(50r/min)30min取样,运用紫外-可见分光光度法测定溶出度,并考察了溶出曲线。结果样品溶出均一性良好,溶出度均>90%。结论本法可用于测定阿托伐他汀钙分散片的溶出度。
Objective To establish a method to determine the dissolution of Atorvastatin Calcium Dispersible Tablets. Methods The oar method （50 r/min） was adopted with the dissolution medium of water and sampling after 30 minutes. The dissolution was determined by UV. The dissolution curve was investigated. Results The dissolution homogeneity of three batches of samples was good and dissolution was all above 90 percent. Conclusion This method can be used to investigate and control the quality of Atorvastatin Calcium Dispersible Tablets.
出处
《食品与药品》
CAS
2006年第11A期49-51,共3页
Food and Drug
关键词
阿托伐他汀钙分散片
溶出度
测定
Atorvastatin Calcium Dispersible Tablets
dissolution
determination
