摘要
目的利用Cox模型(比例风险模型)多因素分析食管癌放射治疗后与生存和复发相关的预后因素,同时探讨CT分期临床应用的合理性。方法对有完整CT资料的70例食管癌患者进行回顾性分析,选择CT分期在内的7个可能对预后产生影响的因素进行Cox模型多因素分析。结果CT分期、病变位置、近期疗效是食管癌放疗后生存率的主要影响因素,年龄、CT分期、病变位置是食管癌放疗后复发的主要影响因素。结论CT分期在非手术食管癌的治疗中能在一定程度上代替食管癌病理分期,指导临床治疗。
Objective To study the prognostic factors in patients with cancer of the esophagus after radiotherapy using Cox proportional hazard model and to evaluate the validity of CT-staging. Methods The clinical data of 70 cases of esophageal cancer treated with radiotherapy were collected, and seven factors including CT-stage were analyzed using Cox proportional hazard model. Results The major significant factors influencing survival rate after radiotherapy were CT-stage, location of tumor and short-term curative effect, The major significant factors influencing relapse after radiotherapy were CT-stage, location of tumor and age. Conclusions CT-staging can substitute for TNM staging in some ways in non-operative treatment for patients with esophageal cancer.
出处
《中华放射医学与防护杂志》
CAS
CSCD
北大核心
2006年第5期496-498,共3页
Chinese Journal of Radiological Medicine and Protection
关键词
食管癌
放射治疗
COX模型
分期
Esophageal cancer
Radiotherapy
Cox proportional hazard model
Stage
