摘要
目的:探讨家兔内囊出血模型脑温及体温的动态变化,为进一步研究内囊出血条件下的脑循环障碍及脑保护提供参考。方法:采用立体定位方法制作家兔内囊出血模型,应用RM-6240B生物信号采集处理系统连续测定内囊出血前后脑温、直肠温以及血压和颅内压的变化。结果:内囊出血后,脑温降低(与出血前比较:P<0.01)、直肠温无明显变化(与出血前比较:P>0.05),颅内压升高(与出血前比较:P<0.01)、血压下降(与出血前比较:P<0.01)。结论:内囊出血可导致颅压升高,颅内灌注压下降,血液循环受到严重影响,颅内脑组织血流量减低,从而出现局部脑温下降。
Objective：To investigate the dynamic changes of brain temperature and body temperature in internal capsule hemorrhage in rabbits and to provide references for studying disorder of cerebral circulation and protection of brain in internal capsule hemorrhage. Methods： The model of internal capsule hemorrhage was made with stereotaxis method, the changes of brain temperature and body temperature as well as the changes of intracranial pressure （ICP） and blood pressure （BP） before and after internal capsule hemorrhage were detected by the RM-6240B biological signal collecting and processing system. Results：After internal capsule hemorrhage in rabbits, the brain temperature decreased significantly （P〈0. 01）, but the body temperature had no obvious changes （P〈0.05）. After internal capsule hemorrhage in rabbits, the ICP increased significantly （P〈0. 01） ,while the BP decreased significantly （P〈0.01）. Conclusions： Internal capsule hemorrhage can induce increased intracranial pressure and decreased intracalvarium perfusion pressure; confused blood circulation can induce the volume of blood flow of brain tissue decreased, accordingly result in decreasing of brain temperature.
出处
《承德医学院学报》
2006年第4期346-348,共3页
Journal of Chengde Medical University
关键词
内囊出血
脑温
体温
家兔
Internal capsule hemorrhage
Brain temperature
Body temperature
