摘要
创伤应激后,机体原有糖代谢平衡紊乱,糖原分解加快,糖原合成减少,糖异生加强,无氧酵解增多,糖利用抑制。创伤早期血糖升高的主要原因是糖原分解,也可能与糖异生有关;当机体进入代谢起涨期后,糖原分解殆尽,糖原合成不足,此时血糖升高主要来源于糖异生,糖摄取利用障碍也可能是原因之一。本文主要从糖原分解与合成、糖异生、糖酵解、糖摄取等环节综述创伤应激后的糖代谢特点。
The original glycometabolism balance of organism may be disturbed after traumatic stress, which is featured by glycogenolyesis acceleration, glycogensis decrease, glyconeogenesis augmentation, anaerobic glycolysis increase, and inhibition of glucose utilization. In the earlier period of trauma （ the ＂ebb＂ phase of injury） , glycogenolysis acceleration is the major cause of blood glucose increase, and glyconeogenesis may also play a role. When it gradually comes to the ＂flow＂ phase （ a period of high metabolism reactions） , as glycogenolysis is almost exhausted and glycogenesis becomes insufficient, the rising blood glucose mainly results from glyconeogenesis, and may also be accompanied by the inhibition of glucose utilization. This article summarizes the characteristics of glycometabolism after traumatic stress, focusing on glycogenolysis, glycogenesis, glyconeogenesis, glycolysis, and glucose intakes.
出处
《中国临床营养杂志》
2006年第5期316-320,共5页
Chinese Journal of Clinical Nutrition
关键词
创伤
应激
糖代谢
trauma
stress
glycometabolism
