1BONE R C,BALK R A,CERRA F B,et al.Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis[J].Chest,l992,101:1644-1655.
3SHEN Y,SULTANAN C,ARDITI M,et al.Endotoxin Induced Migration of Monocytes and PECAM-1 Phosphorylation are Abrogated by PAF Receptor Antagonists[J].Am J Physiol,1998,275(3):479-486.
5ROSSIGNOL D P,LYNN.TLR4 Antagonists for Endotoxemia and Beyond[J].Curr Opin Investig Drugs,2005,6:496-502.
6POLTORAK A,HE X,SMIRNOVA I,et al.Defective LPS Signaling in C3H/H eJ and C57BL/10ScCr mice:Mutations in Tlr4 Gene[J].Science,1998,282:2085-2088.
7MARCUS D,SAEMANN,THOMAS WEICHART,et al.Tamm-Horsfall Glycoprotein Links Innate Immune Cell Activation with Adaptive Immunity via a Toll-like Receptor-4-Dependent Mechanism[J].The journal of Clinical Investigation,2005,115:468-475.
8JANSSENS S,BEYAERT R,Role of Toll-Like Receptors in Pathogen Recognition[J].Clinlcal Microbiology Reviews,2003,637-646.
9MEDXZHITOV R,PAULA P H,CHARLER A,et al.A Human Homologue of the Drosophila Toll Protein Signals Activation of Adaptive Immunity[J].Nature,1997,388:394-397.
10POLTORAK A,HE X,SMIRNOVAL I,et al.Defective LPS Signaling in C3H/H eJ and C57BL/10ScCr Mice:Mutations in Tlr4 Gene[J].Science,1998,282:2085-2088.
6Shen Y, Sultana C, Arditi M, et al. Endotoxin-induced migration of monocytes and PECAM-1 phosphorylation are abrogated by PAF receptor antagonists [ J ]. Am J Physiol, 1998,275 (3 Pt 1 ) : E479- E486.
7Bucklin SE, Lake P, Logdberg L, et al. Therapeutic efficacy of a polymyxin B-dextran 70 conjugate in experimental model of endotoxemia[J]. Antimicro Agents Chemother, 1995,39(7) : 1462-1466.
8Van der Poll T,Lowry SF.Tumor necrosis factor in sepsis: mediator of multiple organ failure or essential part of host defense? [J] Shock,1995,3(1): 1-12.
9Gunnett CA, Chu Y, Heistod DD, et al. Vascular effects of LPS in mice deficient in expression of the gene for inducible nitric oxide synthase[J] .Am J Physiol, 1998,275(2 Pt 2):H416-421.
10Weber C,Rajnoch C,Loth F, et al.The microspheres based detoxification system (MDS). A new extracorporeal blood purification technology based on recirculated microspherical adsorbent particles[J]. Int J Artif Organs, 1994,17( 11 ) : 595-602.
8ZHANGJ, KAAS1K K, BLACKBURN M R. et al., Con?stant darkness is a circadian metabolic signal in mammals[J]. Nature, 2006,4?39(7074) :340-343.
9TAO Z, ZHAO Z, LEE C C. 5'-Adenosine monophosphate in?duced hypothermia reduces early stage myocardial ischemia! reperfusion injury in a mouse model[J]. AmJ Transl Res, 2011,3(4) :351-361.
10ZHANG F, WANG S, LUO Y, et al. When hypothermia meets hypotension and hyperglycemia: I he diverse effects of a?denosine 5'-monophosphate on cerebral ischemia in rats[J].J Cereb Blood Flow Metab, 2009,29(5): 1022-1034.
