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组织蛋白酶B在大肠肿瘤中的表达与临床应用

Cathepsin B expression and its clinical applications in colorectal neoplasms
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摘要 组织蛋白酶B(CB)是存在于人体正常组织的一种半胱氨酸蛋白酶,与肿瘤的侵袭和转移密切相关。新的证据认为CB在癌前状态中同样表达升高,为大肠癌的早期诊断和治疗开辟了新的途径。 Cathepsin B（CB） is a well-known lysosomal cysteine protease which has been studied in association with cancer invasion and metastasis. Present studies show that CB activity is significantly high in eoloreetal cancer and its pre-cancerous conditions ,which break a new path for colorectal cancer＇s early diagnosis and therapy.
作者 马菲菲 张庆瑜
机构地区 天津医科大学总医院消化内科
出处 《国际肿瘤学杂志》 CAS 2006年第10期789-792,共4页 Journal of International Oncology
关键词 结直肠肿瘤 组织蛋白酶B 诊断 治疗 Colorectal neoplasms Cathepsin B Diagnosis Therapy
分类号 Q814.9 [生物学—生物工程] Q789 [生物学—分子生物学]
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国际肿瘤学杂志
2006年 第10期

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