摘要
利用相转移催化反应,由苯甲醛、氯仿和氨合成了医药中间体(±)-α-氨基苯乙酸,其化学产率为72%.
With the reaction of Chloroform,benzadehyde and aqueous ammonia in the presence of four phosphoninum salts and lihium chloride,the medical intermediate + -a-amino-phenylacetic acid is prepared,and the chemical yielder is 72%.
关键词
季Lin盐
相转移催化
中间体
氨基苯乙酸
药物
Phosphoninum salt Phase transfer catalysis Intermediate(±)-α- Amino-phenylacetic acid
