摘要
目的:探讨煨葛根茯苓汤对小儿轮状病毒(RV)肠炎肠道分泌型IgA(sIgA)的影响以及对心肌损害的保护作用。方法:分时段检测35例经煨葛根茯苓汤治疗的RV肠炎患儿的肠道sIgA含量及血清心肌酶含量,并与未经煨葛根茯苓汤治疗的30例同期患儿的检验结果相对照。结果:与对照组相比,第3d治疗组AST、LDH检测值明显降低(P<0.05),而CK、CK-MB检测值差异无显著性;第5d治疗组各项检测值均显著低于对照组(P<0.01或P<0.05);第7d治疗组各项指标均已基本正常,对照组仅CK-MB检测值基本正常。大便sIgA测定显示,治疗组第5d和第7d测定值显著高于对照组(P<0.05)。结论:煨葛根茯苓汤能促进心肌酶的恢复,减轻RV感染导致的心肌损害;能激发肠道组织产生更多的sIgA,加快清除病毒,起到保护脏器组织的作用。
Objective ：To study Weigegen Fuling Tang to serum level of AST, LDH, CK, CK-MB and the sIgA content in stool specimens in children with RV enteritis. Methods ： The serum level of AST, LDH, CK, CK- MB and the sIgA content in stool specimens in 65 cases with RV enteritis were examined. As the treatment group, 35 cases were treated with Weigegen Fuling Tang, and the others being contrast group were treated with convention.Results：Comparing to the contrast group,the serum level of AST,LDH in treatment group were significant lower since the 3rd day（P 〈 0.05）, and the serum level of CK, CK-MB were significant lower since the 5th day（P 〈 0.05 or P〈0.01 ）. The sIgA content of the stool specimens collected from treatment group was remarkably higher than that in contrast group（P 〈 0.05）.Conclusion：It is more rapid that the serum l.evel of＂ AST, LDH, CK and CK-MB in treatment group come to normal. The intestine tissues of the eases treated with Weigegen Fuling Tang can secret more sIgA to against RV.
出处
《中医儿科杂志》
2006年第6期38-40,共3页
Journal of Pediatrics of Traditional Chinese Medicine
基金
佛山市卫生局立项课题(2006234)
