摘要
目的建立半夏厚朴泡腾片中厚朴酚、和厚朴酚含量的测定方法。方法以依利特C18（4．6mm×200mm，5μm）色谱柱分离厚朴酚、和厚朴酚，流动相甲醇-水-乙腈（31，5：38.5：30.0），检测波长294nm。结果线性范围：厚朴酚0．54-13.61μg，r=0．9997（n=7），和厚朴酚0.11-2.82μg，r=0．9997（n=7）。厚朴酚平均回收率100.92％，SRD=1．79％（n=6），和厚朴酚平均回收率101．23％，RSD=1.79％（n=6）。结论该方法简便易行，稳定性较好。
Objective To establish a method for determining the content of magnolol and honokiol in Banxia-Houpu effervescent tablets. Methods Magnolol and honokiol were separated with Elite C18 column（4.6 mm × 200 mm,5μm） and detected at 294 nm, using methanol-acetonitrile-water （31.5： 38.5： 30.0）as mobile phase. Results The standard curves for magnolol and honokiol were linear in the range of 0.54 - 13.61 μg （r = 0. 999 7） and 0.11 - 2.82 μg （r = 0. 999 7）. The average recoveries of magnolol and honokiol were 100.92% （RSD = 1.79% ） and 101.23% （RSD = 1.79% ）. Conclusion The method is simple and quick, which is suitable for practical use.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2006年第11期2209-2210,共2页
Lishizhen Medicine and Materia Medica Research
